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Results for “oHCM”

26 trials

Showing 20 of 26 results

Not applicableActive Not RecruitingNCT07107373
What this trial is testing

Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 150
Not applicableStudy completedNCT06609382
What this trial is testing

Left Ventricular Mass Index Predicts Clinical Outcomes in Patients with Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Changrong Nie 490
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Not applicableStudy completedNCT07529938
What this trial is testing

Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Obstructive Hypertrophic Cardiomyopathy (oHCM)
Chinese Academy of Medical Sciences, Fuwai Hospital 222
Large-scale testing (Phase 3)Study completedNCT06116968
What this trial is testing

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Corxel Pharmaceuticals 40
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Not applicableLooking for participantsNCT07361289
What this trial is testing

Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 500
Large-scale testing (Phase 3)Looking for participantsNCT06412666
What this trial is testing

Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Who this might be right for
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 55
Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Not applicableActive Not RecruitingNCT06372457
What this trial is testing

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Bristol-Myers Squibb 331
Not applicableLooking for participantsNCT07383025
What this trial is testing

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 200
Not applicableLooking for participantsNCT06023186
What this trial is testing

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Michael Ayers 20
Large-scale testing (Phase 3)Study completedNCT05767346
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 175
Large-scale testing (Phase 3)Enrolling By InvitationNCT04848506
What this trial is testing

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

Who this might be right for
Symptomatic Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 900
Large-scale testing (Phase 3)Study completedNCT05186818
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 282
Early research (Phase 1)Study completedNCT04783766
What this trial is testing

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Who this might be right for
Obstructive Hypertrophic CardiomyopathyHealthy Adult Subjects
Corxel Pharmaceuticals 28
Not applicableStudy completedNCT06338202
What this trial is testing

Real-World Effectiveness of Mavacamten in Canada

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 115
Testing effectiveness (Phase 2)Looking for participantsNCT05836259
What this trial is testing

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Who this might be right for
Hypertrophic Cardiomyopathy
Tenaya Therapeutics 30
Not applicableLooking for participantsNCT05489705
What this trial is testing

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 1,700
Early research (Phase 1)Study completedNCT03767855
What this trial is testing

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Who this might be right for
Symptomatic Obstructive Hypertrophic CardiomyopathyHealthy Subjects
Cytokinetics 114
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