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Results for “or Severe Renal Impairment”

70 trials

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Showing 20 of 70 results

Post-approval studies (Phase 4)UnknownNCT00837057
What this trial is testing

Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury

Who this might be right for
Severe SepsisSeptic ShockAcute Kidney Injury
Asan Medical Center 60
Post-approval studies (Phase 4)Study completedNCT02864199
What this trial is testing

Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Combination Therapy in Participants With Chronic Hepatitis C (CHC) and Various Degrees of Renal Impairment

Who this might be right for
Hepatitis C, Chronic
Hoffmann-La Roche 63
Large-scale testing (Phase 3)Study completedNCT04119843
What this trial is testing

Safety and Diagnostic Efficacy of Mangoral in Participants With Focal Liver Lesions and Reduced Kidney Function

Who this might be right for
Known or Suspected Focal Liver LesionsSevere Renal Impairment
Ascelia Pharma AB 87
Large-scale testing (Phase 3)Active Not RecruitingNCT06297603
What this trial is testing

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Who this might be right for
Type 2 Diabetes
Eli Lilly and Company 320
Early research (Phase 1)Ended earlyNCT02679131
What this trial is testing

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

Who this might be right for
Relapsed/Refractory Solid Tumors/Hematological Malignancies
Acrotech Biopharma Inc. 18
Testing effectiveness (Phase 2)Study completedNCT02045017
What this trial is testing

Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency

Who this might be right for
Multiple Myeloma
Celgene 81
Testing effectiveness (Phase 2)Looking for participantsNCT04580420
What this trial is testing

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Who this might be right for
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 28
Early research (Phase 1)Study completedNCT01934166
What this trial is testing

Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment and in Healthy Subjects

Who this might be right for
Renal Impairment
H. Lundbeck A/S 32
Large-scale testing (Phase 3)Study completedNCT01087502
What this trial is testing

Safety and Efficacy of Linagliptin in Type-2-diabetes Mellitus Patients With Moderate to Severe Renal Impairment

Who this might be right for
Diabetes Mellitus, Type 2
Boehringer Ingelheim 241
Early research (Phase 1)Study completedNCT01442259
What this trial is testing

An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects

Who this might be right for
Mild Moderateor Severe Renal Impairment
Novartis Pharmaceuticals 48
Post-approval studies (Phase 4)Ended earlyNCT01104662
What this trial is testing

Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment

Who this might be right for
Complicated Skin and Skin Structure InfectionsS. Aureus BacteremiaRenal Impairment
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 92
Large-scale testing (Phase 3)Study completedNCT03011450
What this trial is testing

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Who this might be right for
Severe Hypertriglyceridemia
Kowa Research Institute, Inc. 471
Early research (Phase 1)Study completedNCT05704556
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment

Who this might be right for
Pain
Vertex Pharmaceuticals Incorporated 38
Large-scale testing (Phase 3)Study completedNCT02207088
What this trial is testing

Ombitasvir/ABT-450/Ritonavir and Dasabuvir With or Without Ribavirin in HCV Genotype 1-Infected Adults With Chronic Kidney Disease

Who this might be right for
Chronic Hepatitis CHepatitis C VirusCompensated Cirrhosis+2 more
AbbVie 68
Early research (Phase 1)Study completedNCT00791401
What this trial is testing

The Pharmacokinetics of ER OROS Paliperidone in Volunteers With Normal or Impaired Renal Function

Who this might be right for
SchizophreniaRenal Impairment
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 47
Not applicableUnknownNCT01685086
What this trial is testing

Surveillance and Follow-up for Latent Tuberculosis Infection and Observation of the Effect of Prophylactic Latent Tuberculosis Treatment in Patients With Severe Chronic Kidney Disease or Receiving Long-term Dialysis

Who this might be right for
To Determine the Prevalence of Latent Tuberculosis in Each GroupTo Monitor the Occurrence of Active Tuberculosis
National Taiwan University Hospital 500
Large-scale testing (Phase 3)Ended earlyNCT02647255
What this trial is testing

Trial of Plasma Exchange for Severe Crescentic IgA Nephropathy

Who this might be right for
Glomerulonephritis, IGAKidney DiseasesAcute Renal Insufficiency+1 more
Peking University First Hospital 10
Early research (Phase 1)Study completedNCT00442871
What this trial is testing

Study Of SB-497115 in Healthy Subjects and Subjects With Mild, Moderate or Severe Renal Impairment

Who this might be right for
Purpura, Thrombocytopaenic, Idiopathic
GlaxoSmithKline 29
Early research (Phase 1)Study completedNCT00567047
What this trial is testing

Pharmacokinetic Study of Vildagliptin in Patients With Renal Impairment

Who this might be right for
Type-2 Diabetes
Novartis 96
Large-scale testing (Phase 3)Study completedNCT02512068
What this trial is testing

A Phase 3, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 3, Multicenter, Open-label, Long-term Study of SYR-472 (25 mg) in Patients With Type 2 Diabetes Mellitus Complicated by Severe Renal Impairment or End-stage Renal Disease

Who this might be right for
Type 2 Diabetes Mellitus
Takeda 107
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