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Results for “pMMR”

171 trials

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Showing 20 of 171 results

Testing effectiveness (Phase 2)Study completedNCT05510895
What this trial is testing

Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer

Who this might be right for
Colorectal CancerColon CancerBRAF V600E+2 more
AIO-Studien-gGmbH 2
Large-scale testing (Phase 3)Looking for participantsNCT05768503
What this trial is testing

Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 176
Testing effectiveness (Phase 2)UnknownNCT06304987
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 50
Large-scale testing (Phase 3)Active Not RecruitingNCT06746116
What this trial is testing

Evaluate the Use of Durvalumab in Combination With Platinum-based Chemotherapy Followed by Durvalumab With Olaparib as First-line Treatment in Advanced or Recurrent Endometrial Cancer in Spain

Who this might be right for
Advanced or Recurrent Endometrial Cancer
AstraZeneca 45
Testing effectiveness (Phase 2)UnknownNCT06239870
What this trial is testing

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

Who this might be right for
Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
Yunnan Cancer Hospital 35
Testing effectiveness (Phase 2)UnknownNCT05160727
What this trial is testing

Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer

Who this might be right for
Mismatch Repair-proficientColorectal Cancer MetastaticMicrosatellite Stable
Zhejiang Cancer Hospital 44
Testing effectiveness (Phase 2)Looking for participantsNCT07718490
What this trial is testing

Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 43
Testing effectiveness (Phase 2)Looking for participantsNCT07133750
What this trial is testing

PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

Who this might be right for
CRC (Colorectal Cancer)
Biotheus Inc. 100
Testing effectiveness (Phase 2)UnknownNCT04659382
What this trial is testing

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerpMMRMSS+2 more
Federation Francophone de Cancerologie Digestive 52
Testing effectiveness (Phase 2)Looking for participantsNCT06864013
What this trial is testing

SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Zhejiang University 116
Not applicableLooking for participantsNCT04504006
What this trial is testing

European Collaborative Multicenter Observational Study: Modular Treatment With PMMR and Targeted Compartmental Pelvic Lymphadenectomy Followed by Therapeutic Pelvic and Paraaortic Lymphadenectomy in Node Positive Disease for Locoregional Control in Endometrial Cancer FIGO Stages I-III

Who this might be right for
Endometrial Cancer
Dr. Paul Buderath 500
Testing effectiveness (Phase 2)Looking for participantsNCT05872685
What this trial is testing

Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05)

Who this might be right for
Adenocarcinoma of the StomachAdenocarcinoma of Esophagogastric JunctionProficient Mismatch Repair
Yu jiren 314
Testing effectiveness (Phase 2)Looking for participantsNCT06829355
What this trial is testing

"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"

Who this might be right for
MCRC
Beijing Friendship Hospital 52
Testing effectiveness (Phase 2)Looking for participantsNCT06266832
What this trial is testing

The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma

Who this might be right for
Rectal Adenocarcinoma
Sir Run Run Shaw Hospital 30
Testing effectiveness (Phase 2)UnknownNCT05588297
What this trial is testing

Preoperative Nivolumab Plus Bevacizumab Combined With Chemotherapy Before Surgery in Patients With pMMR/MSS Colorectal Cancer Liver Metastases

Who this might be right for
Colorectal Cancer Liver Metastases
Shanghai Changzheng Hospital 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381309
What this trial is testing

Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM

Who this might be right for
CRCLiver Metastasis Colon Cancer
Jun Huang 114
Testing effectiveness (Phase 2)Looking for participantsNCT06856837
What this trial is testing

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 140
Testing effectiveness (Phase 2)UnknownNCT05970302
What this trial is testing

XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC

Who this might be right for
TislelizumabBevacizumabOxaliplatin+5 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 52
Testing effectiveness (Phase 2)Looking for participantsNCT05742425
What this trial is testing

Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases

Who this might be right for
Unresectable Colon Cancer Peritoneal MetastasesPMMR/Ras/BRAF Wild-type
Second Affiliated Hospital, Zhejiang University, School of Medicine 30
Testing effectiveness (Phase 2)Looking for participantsNCT07550088
What this trial is testing

BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases

Who this might be right for
Colorectal Cancer Metastatic
Darren Sigal, MD 17
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