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Results for “pMMR/MSS”

114 trials

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Showing 20 of 114 results

Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06014944
What this trial is testing

Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody

Who this might be right for
Rectal Cancer
Changhai Hospital 30
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Looking for participantsNCT05731726
What this trial is testing

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Who this might be right for
pMMRMSSMSI-L+1 more
Zhejiang University 50
Early research (Phase 1)Looking for participantsNCT07510308
What this trial is testing

Clinical Study of MSH2-/- Tumor Cell Vaccines for Advanced pMMR Colorectal Cancer Patients

Who this might be right for
pMMR/MSS Advanced Colorectal Cancer
West China Hospital 9
Testing effectiveness (Phase 2)Looking for participantsNCT07448142
What this trial is testing

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Sun Yat-sen University 50
Testing effectiveness (Phase 2)UnknownNCT04527068
What this trial is testing

QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Second Affiliated Hospital, School of Medicine, Zhejiang University 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07394192
What this trial is testing

Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer

Who this might be right for
Rectal CancerRadiotherapyPD-1 Inhibitor
Peking University Cancer Hospital & Institute 44
Testing effectiveness (Phase 2)Looking for participantsNCT06830239
What this trial is testing

Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer

Who this might be right for
Colon Cancer Stage III
Universitaire Ziekenhuizen KU Leuven 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07527520
What this trial is testing

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial

Who this might be right for
Rectal CancerModerately Hypofractionated RadiotherapySerplulimab+1 more
Fudan University 165
Not applicableNot Yet RecruitingNCT06823323
What this trial is testing

The Study on the Efficacy and Safety of Lactobacillus Johnsonii in Combination with CapeOX and Pembrolizumab for the Treatment of MSS/pMMR Metastatic Colorectal Cancer.

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Second Affiliated Hospital, School of Medicine, Zhejiang University 150
Testing effectiveness (Phase 2)Looking for participantsNCT07230639
What this trial is testing

Node-Sparing Hypofractionated Radiotherapy Plus Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Randomized, Phase II Trial

Who this might be right for
Neoadjuvant TherapiesImmune Checkpoint TherapyRadiotherapy
Sixth Affiliated Hospital, Sun Yat-sen University 52
Large-scale testing (Phase 3)Looking for participantsNCT06733038
What this trial is testing

FOLFOXIRI Plus Bevacizumab With or Without Atezolizumab as 1st Line Treatment of pMMR and IS IC-High Metastatic Colorectal Cancer Patients.

Who this might be right for
Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 238
Testing effectiveness (Phase 2)Looking for participantsNCT06930118
What this trial is testing

The Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparomlimab and Tuvonralimab for the Treatment of Advanced Colorectal Cancer in Third-line Therapy and Subsequent Lines.

Who this might be right for
Advanced Colorectal Cancer in the Third-line Treatment and BeyondpMMR/MSS Advanced Colorectal Cancer
Shanghai Changzheng Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT07527026
What this trial is testing

A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Chinese PLA General Hospital 44
Testing effectiveness (Phase 2)Looking for participantsNCT06543836
What this trial is testing

CtDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 68
Testing effectiveness (Phase 2)Looking for participantsNCT07026422
What this trial is testing

Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT)

Who this might be right for
Rectal Malignant Neoplasms
Shandong Cancer Hospital and Institute 54
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07007767
What this trial is testing

Exploring Sintilimab + Bevacizumab + Decitabine for Advanced pMMR/MSS Colorectal Cancer (After 2+ Prior Therapies）

Who this might be right for
Colorectal Cancer Metastatic
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 32
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940546
What this trial is testing

Neoadjuvant Safety of Sintilimab + XELOX + Bevacizumab in PMMR/MSS CRLM Patients

Who this might be right for
Colorectal Cancer Metastatic
Sun Yat-sen University 36
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