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Results for “pMMR/MSS Advanced Colorectal Cancer”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917
What this trial is testing

Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)

Who this might be right for
Rectal Cancer
Wan He 238
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06599827
What this trial is testing

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC

Who this might be right for
Rectal Cancer
Shanghai Zhongshan Hospital 54
Testing effectiveness (Phase 2)Looking for participantsNCT06829355
What this trial is testing

"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"

Who this might be right for
MCRC
Beijing Friendship Hospital 52
Testing effectiveness (Phase 2)Looking for participantsNCT06558773
What this trial is testing

GSL Synthetase Inhibitor Plus Immune Checkpoint Inhibitor and/or Regorafenib in Previously Treated pMMR/MSS CRC.

Who this might be right for
Colorectal Cancer
Chinese PLA General Hospital 120
Testing effectiveness (Phase 2)Looking for participantsNCT07458529
What this trial is testing

Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant TherapyImmunotherapy+3 more
Seventh Medical Center of PLA General Hospital 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06973343
What this trial is testing

Sintilimab Plus Bevacizumab and Chemotherapy in MSS/pMMR Colorectal With no Liver Metastasis

Who this might be right for
Colorectal Cancer Metastatic
Anhui Provincial Cancer Hospital 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06919510
What this trial is testing

A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Adenocarcinoma
Sun Yat-sen University 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07394192
What this trial is testing

Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer

Who this might be right for
Rectal CancerRadiotherapyPD-1 Inhibitor
Peking University Cancer Hospital & Institute 44
Testing effectiveness (Phase 2)UnknownNCT06543836
What this trial is testing

CtDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 68
Large-scale testing (Phase 3)Looking for participantsNCT05768503
What this trial is testing

Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 176
Testing effectiveness (Phase 2)Looking for participantsNCT07279077
What this trial is testing

Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial

Who this might be right for
Colon CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 38
Testing effectiveness (Phase 2)Ended earlyNCT06834399
What this trial is testing

TATE and KN046 in MCRC

Who this might be right for
Colorectal Cancer with Hepatic Metastases
Zhejiang Raygene Pharmaceuticals Co., Ltd 42
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07527520
What this trial is testing

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial

Who this might be right for
Rectal CancerModerately Hypofractionated RadiotherapySerplulimab+1 more
Fudan University 165
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07175636
What this trial is testing

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)Mismatch Repair-Proficient (pMMR) Rectal CancerNon-metastatic Rectal Cancer
Sun Yat-sen University 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07779694
What this trial is testing

16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer

Who this might be right for
pMMR/MSSLocally Advanced Rectal CarcinomaFasting, Intermittent
Zhejiang University 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06218888
What this trial is testing

A Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver Metastases

Who this might be right for
Colo-rectal Cancer
Fujian Cancer Hospital 17
Testing effectiveness (Phase 2)Looking for participantsNCT07669220
What this trial is testing

A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)

Who this might be right for
Rectal AdenocarcinomaHigh-risk Locally AdvancedShort-course Radiotherapy (SCRT)+2 more
Sixth Affiliated Hospital, Sun Yat-sen University 76
Testing effectiveness (Phase 2)Looking for participantsNCT07448142
What this trial is testing

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Sun Yat-sen University 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT06443671
What this trial is testing

Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Peking University Cancer Hospital & Institute 132
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