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Results for “siRNA”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Testing effectiveness (Phase 2)Study completedNCT00802347
What this trial is testing

I5NP for Prophylaxis of Delayed Graft Function in Kidney Transplantation

Who this might be right for
Delayed Graft FunctionOther Complication of Kidney Transplant
Quark Pharmaceuticals 374
Testing effectiveness (Phase 2)Looking for participantsNCT07271186
What this trial is testing

Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease

Who this might be right for
Diabetic Kidney Disease (DKD)
Regeneron Pharmaceuticals 195
Not applicableStudy completedNCT02864329
What this trial is testing

Small RNA Pathways in Mammalian Gametogenesis

Who this might be right for
Male Infertility
Weill Medical College of Cornell University 182
Testing effectiveness (Phase 2)Study completedNCT03847909
What this trial is testing

Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+2 more
Novo Nordisk A/S 35
Testing effectiveness (Phase 2)Study completedNCT01776658
What this trial is testing

Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain

Who this might be right for
Ocular PainDry Eye Syndrome
Sylentis, S.A. 60
Testing effectiveness (Phase 2)Ended earlyNCT02314052
What this trial is testing

Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 21
Testing effectiveness (Phase 2)Study completedNCT04936035
What this trial is testing

Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension

Who this might be right for
Hypertension
Alnylam Pharmaceuticals 394
Early research (Phase 1)Looking for participantsNCT06585449
What this trial is testing

Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease

Who this might be right for
Huntington's Disease
Alnylam Pharmaceuticals 66
Testing effectiveness (Phase 2)Looking for participantsNCT07465224
What this trial is testing

Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

Who this might be right for
Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals 24
Testing effectiveness (Phase 2)Study completedNCT00259753
What this trial is testing

Safety and Efficacy Study of Small Interfering Ribonucleic Acid (RNA) Molecule (Cand5) to Treat Wet Age-Related Macular Degeneration

Who this might be right for
Macular Degeneration
OPKO Health, Inc. 120
Early research (Phase 1)Not Yet RecruitingNCT07804160
What this trial is testing

A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAL0195 Injection in Participants With or Without Elevated Lipoprotein(a)

Who this might be right for
Elevated Lipoprotein(a)
The Third Xiangya Hospital of Central South University 40
Early research (Phase 1)Study completedNCT01438281
What this trial is testing

Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers

Who this might be right for
Ocular PainDry Eye
Sylentis, S.A. 30
Not applicableApproved For MarketingNCT04125472
What this trial is testing

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria
Alnylam Pharmaceuticals
Early research (Phase 1)Looking for participantsNCT07624071
What this trial is testing

Evaluate ALN-6222 in Participants With Obesity

Who this might be right for
Obesity
Alnylam Pharmaceuticals 88
Testing effectiveness (Phase 2)Study completedNCT05103332
What this trial is testing

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

Who this might be right for
Hypertension
Alnylam Pharmaceuticals 663
Testing effectiveness (Phase 2)Ended earlyNCT04012099
What this trial is testing

The Hypertrophic Scar Prevention of BMT101.

Who this might be right for
Hypertrophic Scar
Hugel 20
Not applicableStudy completedNCT05974345
What this trial is testing

In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease

Who this might be right for
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals 204,691
Testing effectiveness (Phase 2)Looking for participantsNCT05876312
What this trial is testing

Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
ADARx Pharmaceuticals, Inc. 50
Early research (Phase 1)Looking for participantsNCT07444580
What this trial is testing

PrP-targeting siRNA Safety & Mechanism Study

Who this might be right for
Prion Disease
Broad Institute of MIT and Harvard 30
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