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Results for “siRNA”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT04270760
What this trial is testing

Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study

Who this might be right for
Cardiovascular Disease
Amgen 281
Early research (Phase 1)Study completedNCT07412080
What this trial is testing

EDP167 in Healthy Volunteers and Subjects With Mild Dyslipidemia

Who this might be right for
Healthy Adult Male and Female VolunteersMild Dyslipidemia
Eddingpharm (Zhuhai) Co., Ltd. 40
Testing effectiveness (Phase 2)Study completedNCT05184127
What this trial is testing

Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Moderate COVID-19

Who this might be right for
COVID-19
National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia 156
Early research (Phase 1)Study completedNCT00716014
What this trial is testing

Study of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia Congenita

Who this might be right for
Pachyonychia Congenita
Pachyonychia Congenita Project 1
Testing effectiveness (Phase 2)Study completedNCT00306904
What this trial is testing

Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema

Who this might be right for
Diabetic Macular Edema
OPKO Health, Inc. 48
Testing effectiveness (Phase 2)Looking for participantsNCT05648214
What this trial is testing

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Who this might be right for
Healthy VolunteersMetabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Regeneron Pharmaceuticals 172
Testing effectiveness (Phase 2)Ended earlyNCT00395057
What this trial is testing

A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degeneration

Who this might be right for
Choroid NeovascularizationAge-Related Macular Degeneration
Allergan 138
Testing effectiveness (Phase 2)Study completedNCT05637255
What this trial is testing

A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular Age-related Macular Degeneration (AMD)

Who this might be right for
Wet Macular DegenerationNeovascular Age-related Macular DegenerationMacular Degeneration
Sylentis, S.A. 99
Testing effectiveness (Phase 2)Active Not RecruitingNCT06845202
What this trial is testing

Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Who this might be right for
Obese or Overweight Healthy VolunteersType 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals 105
Early research (Phase 1)Active Not RecruitingNCT01591356
What this trial is testing

EphA2 siRNA in Treating Patients With Advanced or Recurrent Solid Tumors

Who this might be right for
Advanced Malignant Solid Neoplasm
M.D. Anderson Cancer Center 49
Early research (Phase 1)Not Yet RecruitingNCT07583914
What this trial is testing

Safety, Tolerability, and Preliminary Antitumor Activity of Non-Cationic Peptide-CD47 siRNA in Advanced Solid Tumors

Who this might be right for
Solid Tumor CancerMetastasesHead and Neck Cancer
West China Hospital 9
Testing effectiveness (Phase 2)Looking for participantsNCT06154278
What this trial is testing

Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B

Who this might be right for
Chronic Hepatitis B
University of Maryland, Baltimore 10
Testing effectiveness (Phase 2)Study completedNCT01739244
What this trial is testing

Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma

Who this might be right for
Ocular HypertensionOpen Angle Glaucoma
Sylentis, S.A. 80
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07799129
What this trial is testing

Phase 2 Dose-Finding Study Evaluating the Efficacy and Safety of EDP167 in Adults With Mixed Dyslipidemia

Who this might be right for
Mixed Dyslipidemia
Eddingpharm (Zhuhai) Co., Ltd. 144
Large-scale testing (Phase 3)Study completedNCT04152200
What this trial is testing

Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria
Alnylam Pharmaceuticals 21
Early research (Phase 1)Active Not RecruitingNCT06452771
What this trial is testing

A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults

Who this might be right for
Healthy Volunteers With Hyperlipidemia
Regeneron Pharmaceuticals 59
Early research (Phase 1)Study completedNCT05484206
What this trial is testing

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Who this might be right for
Hepatic ImpairmentCirrhosis
Vir Biotechnology, Inc. 88
Not applicableUnknownNCT05438069
What this trial is testing

German Inclisiran Network: Retrospective Registry of Patients Being Treated With the siRNA Inclisiran in Germany

Who this might be right for
Hypercholesterolemia
Jena University Hospital 500
Early research (Phase 1)Study completedNCT05643118
What this trial is testing

Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration

Who this might be right for
Neovascular Age-related Macular Degeneration
Olix Pharmaceuticals, Inc. 21
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