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Results for “the First Line Treatment”

1,928 trials

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Showing 20 of 1,928 results

Large-scale testing (Phase 3)UnknownNCT03958890
What this trial is testing

A Clinical Trial Comparing HLX10 With Placebo Combined With Chemotherapy (Cisplatin + 5-fu) in the First-line Treatment of Locally Advanced/Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Shanghai Henlius Biotech 489
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07753642
What this trial is testing

Golidocitinib Plus Anthracycline-based Therapy for Untreated Nodal T-follicular Helper (TFH) Cell Lymphoma

Who this might be right for
Nodal T-follicular Helper Cell Lymphoma
Sun Yat-sen University 47
Large-scale testing (Phase 3)Looking for participantsNCT06646276
What this trial is testing

Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Who this might be right for
Extensive-Stage Small Cell Lung Cancer
Bristol-Myers Squibb 530
Large-scale testing (Phase 3)Study completedNCT00384176
What this trial is testing

First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX

Who this might be right for
Colorectal Cancer
AstraZeneca 1,814
Large-scale testing (Phase 3)Looking for participantsNCT07315750
What this trial is testing

Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma.

Who this might be right for
Gastric Carcinoma
RemeGen Co., Ltd. 555
Testing effectiveness (Phase 2)Looking for participantsNCT06521866
What this trial is testing

Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer

Who this might be right for
Advanced Colorectal CarcinomaImmunotherapy
Fudan University 208
Testing effectiveness (Phase 2)UnknownNCT04586088
What this trial is testing

Apatinib and Camrelizumab in Recurrent or Metastatic Nasopharyngeal Carcinoma With First-line Treatment Failure

Who this might be right for
Nasopharyngeal CarcinomaRecurrent Nasopharyngeal CarcinomaMetastatic Nasopharyngeal Carcinoma+3 more
Sun Yat-sen University 58
Testing effectiveness (Phase 2)UnknownNCT05522894
What this trial is testing

AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC

Who this might be right for
Unresectable Esophageal Squamous Cell CarcinomaLocally Advanced Esophageal Squamous Cell CarcinomaMetastatic Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences 80
Testing effectiveness (Phase 2)Ended earlyNCT01198548
What this trial is testing

High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer

Who this might be right for
Stage IV Colon CancerStage IV Rectal Cancer
Roswell Park Cancer Institute 10
Early research (Phase 1)Active Not RecruitingNCT07009457
What this trial is testing

A Clinical Study of SHR-1316 (SC) Combined With Carboplatin and Etoposide as First-line Treatment for Extensive Stage Small Cell Lung Cancer

Who this might be right for
Widespread Small Cell Lung Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 24
Testing effectiveness (Phase 2)Looking for participantsNCT06517511
What this trial is testing

Selinexor in Combination With R-CHOP as the First-line Therapy for TP53-mutated DLBCL Patients (Smart Trial)

Who this might be right for
Diffuse Large B Cell Lymphoma
Sun Yat-sen University 42
Testing effectiveness (Phase 2)Ended earlyNCT01531764
What this trial is testing

BIBW 2992 (Afatinib) and Vinorelbine

Who this might be right for
Carcinoma Breast Stage IV
University of Magdeburg 2
Post-approval studies (Phase 4)UnknownNCT05311930
What this trial is testing

Efficacy and Safety of TPO Receptor Agonists in the Treatment of Elderly ITP Patients

Who this might be right for
Primary Immune Thrombocytopenia
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 69
Large-scale testing (Phase 3)WithdrawnNCT04065165
What this trial is testing

Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome

Who this might be right for
Small Intestinal NETCarcinoid Heart Disease
European Organisation for Research and Treatment of Cancer - EORTC
Early research (Phase 1)Looking for participantsNCT06610799
What this trial is testing

Study of IBI363 in Patients with Advanced First-line Gastric Cancer

Who this might be right for
IBI363 + Chemotherapy
Xiangdong Cheng 40
Testing effectiveness (Phase 2)UnknownNCT03403101
What this trial is testing

The Combination Chemotherapy of SIRIOX as First- or Second-Line Chemotherapy for Pancreatic Cancer

Who this might be right for
Carcinoma, Pancreatic Ductal
Fudan University 65
Early research (Phase 1)Study completedNCT00532909
What this trial is testing

Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal Cancer

Who this might be right for
Anal, Colon, and Rectal CancersColorectal NeoplasmsColon/Rectal Cancer
Branimir Sikic 13
Post-approval studies (Phase 4)Ended earlyNCT02968901
What this trial is testing

Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)

Who this might be right for
Pulmonary Arterial Hypertension
Actelion 46
Not applicableStudy completedNCT02624895
What this trial is testing

ObservationaL Study on the Qol of RAS Wild-type mCRC Patients Receiving Anti-EGFR MAbs + FOLFOX or FOLFIRI as 1st Line

Who this might be right for
Metastatic Colorectal Cancer
Amgen 296
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06213519
What this trial is testing

HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis

Who this might be right for
Peritoneal MetastasesGastric Cancer
Sichuan University 69
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