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Results for “x Linked Combined Immunodeficiency”

47 trials

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Showing 20 of 47 results

Testing effectiveness (Phase 2)Study completedNCT01129544
What this trial is testing

Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector

Who this might be right for
Severe Combined Immunodeficiency
David Williams 8
Large-scale testing (Phase 3)Study completedNCT00220766
What this trial is testing

Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients

Who this might be right for
Immunologic Deficiency SyndromeAgammaglobulinemiaSevere Combined Immunodeficiency+2 more
Grifols Therapeutics LLC 100
Testing effectiveness (Phase 2)Study completedNCT03513328
What this trial is testing

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeThalassemiaSickle Cell Disease+13 more
University of Florida 6
Not applicableUnknownNCT01346150
What this trial is testing

Patients Treated for SCID (1968-Present)

Who this might be right for
SCIDADA-SCIDXSCID+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 1,007
Not applicableNo Longer AvailableNCT02915406
What this trial is testing

CliniMACs HUD for T Cell Depletion

Who this might be right for
x Linked Combined Immunodeficiency
University of Miami
Not applicableStudy completedNCT00010361
What this trial is testing

Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders

Who this might be right for
Metabolism, Inborn ErrorsGranulomatous Disease, Chronic
Fred Hutchinson Cancer Center 20
Early research (Phase 1)Study completedNCT00008450
What this trial is testing

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Who this might be right for
Adenosine Deaminase DeficiencyAutosomal Recessive DisorderImmune System Disorder+4 more
Fred Hutchinson Cancer Center 6
Testing effectiveness (Phase 2)Temporarily pausedNCT01512888
What this trial is testing

Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants

Who this might be right for
Severe Combined Immunodeficiency Disease, X-linked
St. Jude Children's Research Hospital 28
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Testing effectiveness (Phase 2)Looking for participantsNCT03217617
What this trial is testing

SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection

Who this might be right for
SCID, X-Linked
Shenzhen Geno-Immune Medical Institute 10
Early research (Phase 1)Looking for participantsNCT03601286
What this trial is testing

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency, X-Linked
Great Ormond Street Hospital for Children NHS Foundation Trust 5
Not applicableUnknownNCT00596999
What this trial is testing

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

Who this might be right for
Hematologic Malignancies
Celgene Corporation 6
Not applicableStudy completedNCT00006335
What this trial is testing

Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 40
Post-approval studies (Phase 4)Study completedNCT00002386
What this trial is testing

Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia

Who this might be right for
HIV InfectionsHemophilia A
Merck Sharp & Dohme LLC 55
Not applicableUnknownNCT00006319
What this trial is testing

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Who this might be right for
Wiskott- Aldrich SyndromeADA Deficient SCID
National Human Genome Research Institute (NHGRI) 266
Not applicableAvailableNCT06731036
What this trial is testing

Expanded Access to CD34+ Selection Utilizing Miltenyi CliniMACS Prodigy® for Patients Receiving Peripheral Blood Stem Cell Transplantations and Stem Cell Boosts

Who this might be right for
Severe Combined ImmunodeficiencyFanconi AnemiaDyskeratosis Congenita+1 more
University of Florida
Not applicableLooking for participantsNCT00128973
What this trial is testing

Evaluation of Patients With Immune Function Abnormalities

Who this might be right for
Chronic Granulomatous Disease (CGD)X-Linked Severe Combined Immune Deficiency (XSCID)Leukocyte Adhesion Deficiency 1 (LAD)+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 3,500
Early research (Phase 1)Ended earlyNCT02231710
What this trial is testing

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Who this might be right for
Primary Immune Deficiency DisordersHemophagocytic LymphohistiocytosisInherited Bone Marrow Failure Syndrome+2 more
Bellicum Pharmaceuticals 1
Testing effectiveness (Phase 2)Looking for participantsNCT01306019
What this trial is testing

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

Who this might be right for
X-linked Severe Combined Immunodeficiency (XSCID)
National Institute of Allergy and Infectious Diseases (NIAID) 40
Testing effectiveness (Phase 2)Looking for participantsNCT05463133
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Who this might be right for
Chronic Granulomatous Disease
National Institute of Allergy and Infectious Diseases (NIAID) 50
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