The Effectiveness of Two Anti-HIV Treatments in HIV-Infected Patients

Inclusion Criteria Concurrent Medication: Allowed: * Antibiotics for bacterial infections as clinically indicated. * Recombinant erythropoietin (EPO) and G-CSF as clinically indicated for grade 3 or worse anemia and neutropenia, respectively. * Antipyretics. * Analgesics. * Allergy medications. * Oral contraceptives. * Nonprescription medications such as vitamins or herbal therapies. Concurrent Treatment: Allowed: * Radiation therapy to local lesion only. * Acupuncture. Patients must have: * HIV seropositivity. * CD4 count \>= 550 cells/mm3. * No ARC or AIDS conditions by CDC criteria. * Consent of parent or guardian if less than 18 years of age. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Presence of factors predisposing to pancreatitis such as active alcoholism. * Other medical conditions that would interfere with study compliance. Concurrent Medication: Excluded: * Other antiretrovirals or systemic immunomodulators. * Systemic corticosteroids. * Systemic cytotoxic chemotherapy. * Intravenous pentamidine. Concurrent Treatment: Excluded: * Radiation therapy except to local lesion. Patients with the following prior conditions are excluded: * History of chronic diarrhea, defined as more than four loose or watery stools on average daily for the past month. * History of grade 2 or worse peripheral neuropathy. * History of pancreatitis. * Bacterial infection requiring antibiotics within 14 days prior to study entry. Prior Medication: Excluded: * Prior HIV therapy with antiretrovirals or systemic immunomodulators. Prior Treatment: Excluded within 2 weeks prior to study entry: * Transfusion. Active substance abuse or alcoholism.