STA-5326 in Crohn's Disease Patients

Inclusion Criteria: * Patients 18-65 years old * Crohn's Disease for 6 months * CDAI scores between 220-450 * +/- 5-ASA, stable dose for \> 2 weeks * +/- Corticosteroids, less than or equal to 40 mg per day with a stable dose for 2 weeks * +/- Infliximab with no treatment within 4 weeks * +/- 6-Mercaptopurine, with a stable dose for 8 weeks * +/- Antibiotics, with a stable dose for 2 weeks Exclusion Criteria: * Patients who have had methotrexate, cyclosporine, or other experimental drug within 3 months of screening * Pregnancy, breast feeding * History of total proctocolectomy with stoma. Previous ileocolectomy would not be a contraindication to the study * Bowel obstruction * Surgical bowel resection within 90 days * Total parenteral nutrition (TPN), CYA, tacrolimus