Docetaxel and PTK787 in Metastatic Breast Cancer Patients and Gynecological Cancer Patients

Inclusion Criteria: * Recurrent gynecological cancers or metastatic breast cancer. Initial diagnosis must be confirmed histologically. * Measurable disease or nonmeasurable disease * Age \> 18 years * ECOG performance 0,1,2 * 4 weeks or greater since major surgery, 3 weeks or greater since chemotherapy * Certain lab values * Negative for proteinuria Exclusion Criteria: * Four or more treatment regimens * History or presence of uncontrolled CNS disease * Prior biologic or immunotherapies less than 3 weeks prior to registration * Prior full field radiotherapy less than 4 weeks or limited field radiotherapy less than 2 weeks prior to registration * Prior therapy with anti-VEGF agents * Peripheral neuropathy with functional impairment \> CTC grade 2 * Pregnant or breast feeding * Concurrent severe and/or uncontrolled medical condition * Chronic renal disease * Acute or chronic liver disease * Impairment of gastrointestinal function or GI disease * Confirmed diagnosis of HIV infection are excluded at the investigators discretion * Therapeutic warfarin sodium or similar oral anticoagulants that are metabolized by the cytochrome p450 system.