A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.528 enrolled

Overview

To demonstrate statistical superiority of the combination of latanoprost and timolol to the individual therapy of latanoprost and timolol based on intraocular pressure measurements at 8 AM, 10 AM, 4 PM at weeks 2, 6 and 12.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

528

Conditions

Open Angle Glaucoma Ocular Hypertension

Interventions

XalacomDRUG

XalatanDRUG

TimololDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Uni- or bilateral diagnosis of primary open angle glaucoma or ocular hypertension on beta-blocker monotherapy or dual therapy in which at least one medication is a beta-blocker for at least 4 weeks prior to screening Exclusion Criteria: * Closed/ barely open anterior chamber angle or history of acute angle closure glaucoma. * History of ALT (Argon Laser Trabeculoplasty) or SLT(selective Laser) within 3 months prior to screening

Locations (64)

Outcomes

Primary Outcomes

The mean IOP measurements obtained in the study eye at each time point.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

Pfizer Investigational Site

Birmingham, Alabama, United States

Pfizer Investigational Site

Flagstaff, Arizona, United States

Pfizer Investigational Site

Artesia, California, United States

Pfizer Investigational Site

Los Angeles, California, United States

Pfizer Investigational Site

Newport Beach, California, United States

Pfizer Investigational Site

Sacramento, California, United States

Pfizer Investigational Site

San Francisco, California, United States

Pfizer Investigational Site

Colorado Springs, Colorado, United States

Pfizer Investigational Site

Gainesville, Florida, United States

Pfizer Investigational Site

Lecanto, Florida, United States

...and 54 more locations