To determine the effect of Armodafinil (Nuvigil) on fatigue and sleep in sarcoidosis.
The study will be divided into two halves. Patients will receive either drug or placebo in the first half. Patients receiving active drug will be started at one dose and it can be increased at the second visit. Those patients randomized to placebo will also have their dose adjusted by the investigating physician. The physicians will be blinded as to whether the patient is receiving drug or placebo. In the second half of the study, patients will receive the opposite treatment. Patients will have complete detailed questionnaires regarding their fatigue, sleepiness, and overall quality of life. They will have sleep studies done at the start and after each half of the study to determine the effect of therapy on sleepiness.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
20
Dosage 150-250 mg
Placebo
University of Cincinnati
Cincinnati, Ohio, United States
To determine the effect of Armodafinil (Nuvigil) on fatigue and sleep in sarcoidosis.
Time frame: Prospective
To determine the effect of Armodafinil (Nuvigil) on pulmonary function in sarcoidosis.
Time frame: Prospective
To determine the safety and tolerability of Armodafinil (Nuvigil) in sarcoidosis.
Time frame: Prospective
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