We will identify the influence of long-term treatment of Pitavastatin compared to non-treatment control group on the metabolic syndrome by evaluation of a change of metabolic syndrome component score. And we will additionally observe the changes of CVD risk factors like lipid profile, abdominal fat, insulin resistance and so on.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
187
Pitavastatin 2mg daily once
conducting mainly exercises and diet
Seoul National University Bundang Hospital
Bundang-gu, Gyeonggi-do, South Korea
Hanyang Univ. Guri Hospital
Guri-si, Gyeonggi-do, South Korea
A change of metabolic syndrome risk component
Time frame: 48week
Changes of cardiometabolic profiles : lipid profiles, hs-CRP, adiponectin, HMW adiponectin
Time frame: 48week
Changes of abdominal visceral fat
Time frame: 48week
Changes of insulin resistance : OGTT(75g), HOMA
Time frame: 48week
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