Studies on Aldosterone and Vascular Function

Yale University20 enrolled

Overview

A randomized crossover trial to determine the effects of sodium loading and aldosterone infusion on endothelial function in normal subjects.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

QUADRUPLE

Enrollment

4 hour infusion

placebo

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy subjects age \>18 years Exclusion Criteria: * Any chronic medical disease or chronic use of medications

Yale University School of Medicine

New Haven, Connecticut, United States

Flow mediated dilation brachial artery

Time frame: 0 and 4 hours

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