Statin is an effective drug to treat hyperlipidemia (hypercholesterolemia), and it rarely leads to hepatic damage to the patients with hepatic disorder. For these patients, intensive monitoring is required.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
pitavastatin 2mg per daily
atorvastatin 10mg per daily
Proportion of the subjects whose ALT levels were over CTCAE grade II after treatment
Time frame: 12 weeks
1.Changes in ALT after treatment
Time frame: 12 weeks
2.Changes in AST after treatment
Time frame: 12 weeks
3.Changes in LDL-C, TC, TG and HDL-C after treatment
Time frame: 12 weeks
4.Changes in fat in liver after treatment
Time frame: 12 weeks
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