The purpose of this study is to determine if droperidol is equally as effective as metoclopramide for treatment of primary headaches in the Emergency Department.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
19
Droperidol 1.25 mg IV x 1, may repeat 0.625 mg if needed at 60 minutes
Metoclopramide 20 mg IV infusion q30 minutes as needed with a maximum of 4 doses + Diphenhydramine 25 mg IV injection x 1 given with the first dose of metoclopramide IV infusion and repeated x 1 given with the third metoclopramide IV infusion.
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Pain Scale (Numerical Rating Scale for Pain)
Numerical Rating Scale for Pain on a scale of 0-10 with 10 representing the worst pain
Time frame: Change in pain scores at 60 minutes from baseline as measured on the Numerical Rating Scale for Pain (NRS)
Length of Stay
Time frame: Participants will be followed for the duration of their emergency department visit after the initiation of treatment (Average Length of stay in minutes)
24 Hour Pain Score
24 hour pain score (follow-up phone call)
Time frame: 24 hours after discharge from ED
Adverse Effects
Frequency of adverse effects in each arm
Time frame: From the time when the treatment is initiated until the 24 hour follow-up phone survey
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