Efficacy, Safety and Tolerability Study of N1539 in Subjects After Abdominal Laparoscopic Surgery

Inclusion Criteria: * Planning to undergo elective abdominal laparoscopic surgery involving a single site/organ and does not have intraperitoneal metastases suspected or identified Exclusion Criteria: * Use of ketorolac is contraindicated * Use of general anesthesia is contraindicated * Has a medical condition that could adversely impact subject participation * Has diabetes mellitus and glycosylated hemoglobin (HbA1c) \>9.5 or history of prolonged uncontrolled diabetes * Body mass index (BMI) less than 18 or greater than 35 * Has a history of intolerance or allergic reactions to non-steroidal anti-inflammatory drugs (NSAIDs), Cox-2 inhibitors, aspirin or other salicylates * Known or suspected sleep apnea * History of Hepatitis B or C * Has a psychiatric disorder that impairs capability of subject to report pain * Known to have chronic obstructive pulmonary disease (COPD) with carbon dioxide retention or chronic hypoxemia