Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure

Inclusion Criteria: * Prehypertensive male and female subjects with SBP =120-140 mmHg or DBP =80-90 mmHg (as determined by seated office BP). * Plasma uric acid level ≥5 mg/dl * Ages 18-50 * non-smokers * Subjects will need to remain in the San Diego area for the duration of the study and be accessible by telephone or email. Exclusion Criteria: * no current smoking in the prior 6 months. * Any history of any serious medical conditions requiring close monitoring from physicians- such as liver impairment, chronic kidney disease, or diabetes mellitus. Participants not currently under the care of a physician for these conditions will be eligible for the study. * Any history of gout, hypertension, hypercholesterolemia, morbid obesity. * Any history of use xanthine oxidase inhibitors, antihypertensives, antiglycemic, and cholesterol lowering medications * any history of illicit drug use within the last 6 months