To Compare the Efficacy of Combined Tenofovir Plus Telbivudine vs Tenofovir Alone in Patients With Spontaneous Reactivation of Hepatitis B

Inclusion Criteria: * Reactivation of CHB characterized by a rise in ALT level \>5 times upper limit of normal along with HBV DNA level \>10\^5 copies/ mL (\> 1.8 X 10\^4 IU/mL). Exclusion Criteria: 1. Superinfection with other viruses (hepatitis E, A, D, or C) 2. other causes of chronic liver failure 3. coexistent hepatocellular carcinoma (HCC) 4. portal vein thrombosis 5. coexistent renal impairment 6. pregnancy 7. coinfection with human immunodeficiency virus (HIV) 8. patients who had received a previous course of any antiviral, immunomodulator or cytotoxic/immunosuppressive therapy for chronic hepatitis or other illness within at least the preceding 12 months.