Tenoxicam for Intrapartum Analgesia

Ain Shams Maternity Hospital100 enrolled

Overview

The aim of this study is to assess whether tenoxicam is as effective as pethidine for analgesia during the first stage of labor.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

100

Conditions

Analgesia Obstetrical

Interventions

TenoxicamDRUG

PethidineDRUG

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Primiparity * Active phase of labor (cervical dilatation of 3-5 cm, in the presence of adequate uterine contractions; lasting at least 40 seconds at intervals of 3-4 minutes) * Maternal age between 20-30 years * Singleton term pregnancy (37-42 weeks of gestation) * Vertex-presenting fetus Exclusion Criteria: * Clinical evidence of cephalopelvic disproportion * Scarred uterus; previous cesarean section, hysterotomy or myomectomy * Medical disorders associated with pregnancy, especially gastritis, peptic ulcer, bronchial asthma or renal impairment * Fetal distress * Receiving any regional or parenteral analgesia before recruitment in the study * Known hypersensitivity to the drug family

Outcomes

Primary Outcomes

The efficacy of intravenous tenoxicam to supply adequate analgesia as indicated by changes in the pain intensity score using the visual analog scale

Assessment is to be done and followed up by the investigator at ½, 1, 2, 3 and 4 hours from drug administration. Scores range from 0 \[no pain\] to 10 \[worst possible pain\].

Time frame: 4 hours

Data from ClinicalTrials.gov

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