Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Inclusion Criteria: * Adolescents between 12 to 18 years old must weigh \>60 kg * Patients diagnosed with ABSSSI with at least one systemic sign of infection * Diagnosed with cellulitis, major cutaneous abscess, or wound infections (traumatic or surgical) * Surface redness, edema or induration must be of a minimum surface area of 75 cm2, or extending ≥5 cm from the peripheral margin of the abscess * Suspected or documented ABSSSI caused by a Gram-positive pathogen Exclusion Criteria: * Involving a chronic diabetic foot infection (diabetic foot ulcer) * Involving burns * Involving an anatomical location (e.g. perirectal area) where the incidence of Gram-negative and/or anaerobic pathogen involvement is likely * Documented bacteremia associated with the current ABSSSI * Known severe renal impairment, as indicated by estimated CrCl \<30 mL/min (by Cockcroft-Gault calculation) * Evidence of significant liver disease: ALT \>3x ULN, or direct bilirubin \>ULN; known cirrhosis with decompensation (i.e. Child-Pugh Class B or C disease)