A Randomized, Double-blinded, Multi-center, Phase III Study to Compare The Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 versus HCP1701 in Patients with Hypertension and Dyslipidemia
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
145
Seoul National University Hospital
Seoul, Seoul, South Korea
Change from baseline in LDL-C (%)
Experimental, Active Control 1
Time frame: baseline, 8 weeks
Change from baseline in sitting systolic blood pressure
Experimental, Active Control 2
Time frame: baseline, 8 weeks
Change from baseline in LDL-C (%)
Experimental, Active Control 2
Time frame: baseline, 8 weeks
Change from baseline in sitting systolic blood pressure
Experimental, Active Control 1
Time frame: baseline, 8 weeks
Change from baseline in LDL-C (%)
Time frame: baseline, 4 weeks
Change from baseline in sitting systolic blood pressure
Time frame: baseline, 4 weeks
Change from baseline in TC, HDL-C, TG (%)
Time frame: baseline, 4 weeks, 8 weeks
Change from baseline in sitting distolic blood pressure
Time frame: baseline, 4 weeks, 8 weeks
Proportion of subject achieving LDL-C control
Time frame: baseline, 4 weeks, 8 weeks
Proportion of subjects achieving blood pressure control
Time frame: baseline, 4 weeks, 8 weeks
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Rosuvastatin and Ezetimibe
Proportion of responder for blood pressure
Time frame: baseline, 4 weeks, 8 weeks
Proportion of subject achieving both LDL-C and blood pressure control
Time frame: baseline, 4 weeks, 8 weeks