Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

Phase 3RecruitingNCT04161768

Tanta University80 enrolled

Overview

Norfloxacin versus Norfloxacin with Itopride in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

Comparative Study of Norfloxacin versus Norfloxacin with Itopride in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Spontaneous Bacterial Peritonitis

Interventions

NorfloxacinDRUG

Norfloxacin 400 mg daily

ItoprideDRUG

Itopride 50 mg three times daily

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * cirrhotic patients with ascites who had previous episodes of SBP. Exclusion Criteria: * 1\. Allergy or contraindication for the used drugs. 2. Recent antibiotics therapy in the previous 2 weeks. 3. Patients with hepatocellular carcinoma or other neoplasia. 4. Pregnant and lactating women.

Locations (1)

Sherief Abd-Elsalam

Tanta, Egypt

RECRUITING

Outcomes

Primary Outcomes

Number of bouts of recurrence during treatment.

The recurrence of infection during treatment.

Time frame: 6 months

Central Contacts

Sherief Abd-Elsalam, ass. prof.

CONTACT

00201147773440 sheriefabdelsalam@yahoo.com

sherief abd-elsalam, ass. prof.

CONTACT

00201147773440 sherif_tropical@yahoo.com

Data from ClinicalTrials.gov

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