Anaesthesia and Apoptosis

Assiut University20 enrolled

Overview

Anesthetics cause widespread apoptosis in the developing brain, resulting in neurocognitive abnormalities. However, it is unknown whether anesthesia-induced neurotoxicity occurs in humans because there is currently no modality to assess for neuronal apoptosis in vivo

Study Type

OBSERVATIONAL

Enrollment

Conditions

Apoptosis

Interventions

apoptosisOTHER

study of apoptotic changes due to anaesthesia

Eligibility

Sex: ALLMin age: 1 YearMax age: 10 Years

Medical Language ↔ Plain English

Inclusion Criteria: * congenital heart corrective surgery Exclusion Criteria: * none

Locations (1)

Assiut university

Asyut, Egypt

RECRUITING

Outcomes

Primary Outcomes

apoptotis during anaesthesia

measuring markers of apoptosis pathway

Time frame: 24 hours

Data from ClinicalTrials.gov

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