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Results for “Apoptosis”

530 trials

Showing 20 of 530 results

Post-approval studies (Phase 4)Ended earlyNCT00209287
What this trial is testing

Study of Effects and of Modifications in Apoptosis Regulators Observed After Stopping 5-ASA Treatment in Patients With Inactive Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Ferring Pharmaceuticals 6
Large-scale testing (Phase 3)Active Not RecruitingNCT03164616
What this trial is testing

Study of Durvalumab + Tremelimumab With Chemotherapy or Durvalumab With Chemotherapy or Chemotherapy Alone for Patients With Lung Cancer (POSEIDON).

Who this might be right for
Non Small Cell Lung Cancer NSCLC
AstraZeneca 1,186
Testing effectiveness (Phase 2)UnknownNCT04014101
What this trial is testing

SHR-1210 Plus Apatinib in Patients With Advanced-Stage Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital 40
Testing effectiveness (Phase 2)UnknownNCT03903887
What this trial is testing

Anti-PD1 Antibody-activated TILs in Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Sun Yat-sen University 20
Post-approval studies (Phase 4)Study completedNCT00204334
What this trial is testing

Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients

Who this might be right for
Kidney TransplantationAnemia
University Hospital Muenster 60
Testing effectiveness (Phase 2)WithdrawnNCT03221634
What this trial is testing

Efficacy and Safety Study of Pembrolizumab (MK-3475) in Combination With Daratumumab in Participants With Relapsed Refractory Multiple Myeloma (MK-3475-668/KEYNOTE-668)

Who this might be right for
Multiple Myeloma
Merck Sharp & Dohme LLC
Early research (Phase 1)Study completedNCT02054806
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)

Who this might be right for
Solid Tumor
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Not applicableStudy completedNCT02310087
What this trial is testing

Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures

Who this might be right for
Infertility, Male
University Medical Centre Ljubljana 80
Early research (Phase 1)Study completedNCT00007163
What this trial is testing

Monoclonal Antibody Treatment of Crohn's Disease

Who this might be right for
Crohn's Disease
National Institute of Allergy and Infectious Diseases (NIAID) 40
Large-scale testing (Phase 3)Active Not RecruitingNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 480
Large-scale testing (Phase 3)Active Not RecruitingNCT07000149
What this trial is testing

Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC

Who this might be right for
Advanced Clear Cell Renal Cell Carcinoma
AstraZeneca 1,116
Large-scale testing (Phase 3)Active Not RecruitingNCT03711032
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Who this might be right for
High-risk Non-muscle Invasive Bladder Cancer
Merck Sharp & Dohme LLC 1,397
Large-scale testing (Phase 3)Active Not RecruitingNCT03553836
What this trial is testing

Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 976
Early research (Phase 1)Ended earlyNCT04274907
What this trial is testing

A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Who this might be right for
Non Small Cell Lung CancerCancer
AbbVie 2
Testing effectiveness (Phase 2)WithdrawnNCT03167177
What this trial is testing

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Who this might be right for
Melanoma
ImmunityBio, Inc.
Testing effectiveness (Phase 2)Study completedNCT02879617
What this trial is testing

A Clinical Trial of Durvalumab (MEDI4736) as 1st Line Therapy in Advanced Non-small Cell Lung Cancer Patients

Who this might be right for
Non-Small Cell Lung Cancer NSCLC
Academic Thoracic Oncology Medical Investigators Consortium 47
Testing effectiveness (Phase 2)Study completedNCT02530424
What this trial is testing

"Neo-Adjuvant Treatment With Palbociclib: Effect on Ki67 and Apoptosis Before, During and After Treatment "

Who this might be right for
Breast Neoplasms
Fondazione Michelangelo 102
Testing effectiveness (Phase 2)Study completedNCT02255097
What this trial is testing

Study of MK-3475 (Pembrolizumab) in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Treatment With Platinum-based and Cetuximab Therapy (MK-3475-055/KEYNOTE-055)

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 172
Not applicableEnded earlyNCT03946774
What this trial is testing

Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling

Who this might be right for
Dietary Protein
Washington University School of Medicine 21
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