Modeling Stress-precipitated Vaping Behavior

Clemson University51 enrolled

Overview

The primary aims of this pilot study were to (1) initially validate the applicability of a human laboratory model of relapse initially developed for smokers to e-cigarette users; (2) to use this human laboratory model of lapse behavior to examine the effects of acute psychological stress on vaping-lapse behavior among adults who are experienced, e-cigarette users.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Vaping

Interventions

Control task and Trier Social Stress TaskOTHER

Same as Arm

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * at least 18 years old * e-cigarette users * using ≥1 mL of e-cigarette liquid per day with a nicotine concentration of ≥3mg/ml * had used an e-cigarette for at least three months Exclusion Criteria: * Current smokers * Psychiatric or medical condition based * Using a prescription medication other than birth control

Locations (1)

University of Vermont

Burlington, Vermont, United States

Outcomes

Primary Outcomes

latency to initiate ad-lib vaping session (in minutes)

Time to vaping during the vaping delay task. Range of time delay is 0 minutes to 50 minutes.

Time frame: During the two laboratory sessions which occur within 1 week after screening/baseline.

number of puffs purchased and consumed during the self-administration period

Number of e-cigarette uses purchased during the self-administration phase of the vaping delay task. Range of puffs is 0 to 20.

Time frame: During the two laboratory sessions which occur within 1 week after screening/baseline

Secondary Outcomes

Craving

Craving was measured using a visual analogue scale (VAS) asking "How much do you crave an e-cigarette right now?" with possible responses ranging from 0 (not at all) to 100 (extremely).

Time frame: The VAS will be collected at each laboratory session (within 1 week after screening/baseline) 5 times: baseline (pre task), post task (+15 minutes), decision to smoke (+20 minutes), +30 minutes smoking ab-lib, and +60 minutes during smoking ab-lib

Stress

Stress was measured using a visual analogue scale (VAS) asking: "How stressed or anxious do you feel right now?" with possible responses ranging from 0 (not at all) to 100 (extremely).

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.