Post-approval studies (Phase 4)Study completedNCT02203162What this trial is testingEffect of Electronic Cigarette Use on Cough Reflex SensitivityWho this might be right forCough Montefiore Medical Center 30
Not applicableStudy completedNCT03593239What this trial is testingComparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy SmokersWho this might be right forNicotine DependenceNicotine Dependence, CigarettesTobacco Use+1 more Juul Labs, Inc. 24
Not applicableLooking for participantsNCT06819969What this trial is testingThe Canadian Lung Outcomes in Users of Vaping Devices StudyWho this might be right forSmall Airways DiseasesVapingVaping Related Disorder+2 more University of British Columbia 500
Not applicableStudy completedNCT02328794What this trial is testingRandomized Clinical Trial to Reduce Harm From TobaccoWho this might be right forSmoking Cessation University of Pennsylvania 6,006
Not applicableStudy completedNCT03742817What this trial is testingEffects of e-Cigarettes on Perceptions and BehaviorWho this might be right forElectronic Cigarettes University of Southern California 45
Not applicableStudy completedNCT02664012What this trial is testingComparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine GumWho this might be right forSmoking R.J. Reynolds Vapor Company 71
Not applicableStudy completedNCT04522973What this trial is testingThe Impact of Oral Ethanol and Vaped Ethanol on the Evaluation of ImpairmentWho this might be right forElectronic Cigarette Use Virginia Commonwealth University 12
Not applicableStudy completedNCT05458895What this trial is testingEvaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among YouthWho this might be right forE-cigarette Use Ohio State University Comprehensive Cancer Center 88
Not applicableNot Yet RecruitingNCT07274475What this trial is testingSmoking Harm Reduction Using E-cigarettes and CytisineWho this might be right forTobacco SmokingHarm ReductionNicotine Centre for Addiction and Mental Health 6,000
Not applicableStudy completedNCT06534905What this trial is testingE-cigarette Switching Older AdultsWho this might be right forTobacco UseOpioid Use DisorderTobacco-Related Disorders University of Maryland, Baltimore 36
Not applicableLooking for participantsNCT06239350What this trial is testingYoung Adult Tobacco/Nicotine and Cannabis Co-useWho this might be right forTobacco Use DisorderNicotine Dependence Medical University of South Carolina 350
Not applicableStudy completedNCT05134415What this trial is testingUse Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS ConsumersWho this might be right forElectronic Cigarette Use Cheerain HK Limited 40
Not applicableEnded earlyNCT06503159What this trial is testingHippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot StudyWho this might be right forVaping TeensHealthy Volunteers National Institute on Drug Abuse (NIDA) 14
Not applicableNot Yet RecruitingNCT07612696What this trial is testingImpact of Electronic Cigarette Temperature and Solvent on BiomarkersWho this might be right forOxidative StressTobacco UseElectronic Cigarettes Milton S. Hershey Medical Center 50
Not applicableStudy completedNCT05023096What this trial is testingPotential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol SmokersWho this might be right forElectronic Nicotine Delivery System Flavors Virginia Commonwealth University 71
Large-scale testing (Phase 3)Looking for participantsNCT05257629What this trial is testingAggressive Smoking Cessation Trial (ASAP)Who this might be right forAcute Coronary SyndromeCardiovascular Diseases Sir Mortimer B. Davis - Jewish General Hospital 798
Not applicableStudy completedNCT04522362What this trial is testingModeling Stress-precipitated Vaping BehaviorWho this might be right forVaping Clemson University 51
Post-approval studies (Phase 4)Ended earlyNCT04602494What this trial is testingVarenicline For Nicotine Vaping Cessation In Non Smoker Vaper AdolescentsWho this might be right forVapingNicotine Dependence Massachusetts General Hospital 5
Not applicableStudy completedNCT03839745What this trial is testingShort-Term Cardiovascular Effects of E-Cigarettes: Influence of Device PowerWho this might be right forCardiovascular Risk FactorNicotine Dependence University of California, San Francisco 16
Large-scale testing (Phase 3)Study completedNCT02521662What this trial is testingThe Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking CessationWho this might be right forSmoking Cessation University of Auckland, New Zealand 1,124