Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma

Phase 2CompletedNCT05790577

Ishtiaq Ahmed88 enrolled

Overview

Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma

A comparative study to evaluate Efficacy and tolerability of new lotion in the treatment of Melasma.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Melasma

Interventions

Metformin and Nicotinamide vs Kligman FormulaDRUG

Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 18-50 * No systemic therapy * All Co-morbids Exclusion Criteria: * Pregnancy * Age \>50 * Taking oral treatment for melasma

Locations (1)

PakEmiratesMH

Rawalpindi, Punjab Province, Pakistan

Outcomes

Primary Outcomes

Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma

Efficacy with measurement of MASI score 4 weeks apart

Time frame: 12 weeks

Data from ClinicalTrials.gov

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