Very early researchUnknownNCT06153134What this trial is testingCurcuma Xanthorriza Roxb. 10% Cream for MelasmaWho this might be right forMelasma Universitas Padjadjaran 15
Not applicableUnknownNCT06320314What this trial is testingEfficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 OriginsWho this might be right forHyperpigmentation Cosmetique Active International 60
Post-approval studies (Phase 4)UnknownNCT05099601What this trial is testingSilymarin Cream Versus Combined Silymarin Cream and Microneedling in Treatment of MelasmaWho this might be right forMelasma Assiut University 30
Not applicableNot Yet RecruitingNCT07495748What this trial is testingComparative Evaluation of Topical Metformin and Topical Tranexamic Acid in MelasmaWho this might be right forMelasma Foundation University Islamabad 70
Large-scale testing (Phase 3)Study completedNCT01001624What this trial is testingMelanil in the Treatment of MelasmaWho this might be right forMelasma Catalysis SL 150
Post-approval studies (Phase 4)UnknownNCT03475524What this trial is testingUSE THE SYSTEMIC METFORMIN IN MELASMAWho this might be right forMelasma Assiut University 60
Not applicableStudy completedNCT06616311What this trial is testingEfficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color.Who this might be right forMelasma The Cleveland Clinic 10
Not applicableStudy completedNCT01162850What this trial is testingOral Polypodium Leucotomos for MelasmaWho this might be right forMelasma University of Miami 21
Very early researchWithdrawnNCT02812719What this trial is testingTreatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid PeelWho this might be right forMelasma Boston Medical Center
Large-scale testing (Phase 3)UnknownNCT06010810What this trial is testingThe Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of MelasmaWho this might be right forMelasma Indonesia University 20
Testing effectiveness (Phase 2)WithdrawnNCT06473974What this trial is testingOpen-label, Single-arm, Proof of Concept Study in Subjects with Mild-to-moderate Facial HyperpigmentationWho this might be right forFacial Hyperpigmentation Kayuraeffect, LLP
Not applicableStudy completedNCT01335581What this trial is testingStudy of Laser Treatment of MelasmaWho this might be right forRefractory Mixed Type Melasma ConBio, a Cynosure Company 18
Not applicableEnded earlyNCT05326997What this trial is testingTreatment of Melasma With Yellow Light Compared to Tranexamic AcidWho this might be right forMelasma University of Nove de Julho 21
Not applicableEnded earlyNCT01745224What this trial is testingRevlite Laser System Compared to the Candela Alex TriVantage System Refractory Mixed Type MelasmaWho this might be right forMelasma Cynosure, Inc. 4
Large-scale testing (Phase 3)Study completedNCT05969587What this trial is testingCysteamine Compared to Hydroquinone in MelasmaWho this might be right forMelasma China Medical University Hospital 28
Not applicableLooking for participantsNCT06522984What this trial is testingFractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic AcidWho this might be right forRefractory Melasma Egymedicalpedia 45
Testing effectiveness (Phase 2)Study completedNCT01085279What this trial is testingFractional Laser as Treatment Option for Various Pigment Disorders (Fractional-3)Who this might be right forPigmentation Disorder Netherlands Institute for Pigment Disorders 29
Post-approval studies (Phase 4)UnknownNCT04823520What this trial is testingTrichloroacetic Acid (TCA) Combined With Microdermabrasion in Treatment of MelasmaWho this might be right forMelasma Assiut University 60
Large-scale testing (Phase 3)UnknownNCT04599205What this trial is testingEvaluation of Laser and Tranexamic Acid in Treatment of MelasmaWho this might be right forMelasma Assiut University 40
Large-scale testing (Phase 3)Not Yet RecruitingNCT07448415What this trial is testingEvaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of MelasmaWho this might be right forMelasma Assiut University 42