Pain Control After Open Radical Nephrectomy: Thoracic Paravertebral Block Versus External Oblique Intercostal Block

Hacettepe University98 enrolled

Overview

This study aims to compare the effects of external oblique intercostal block versus paravertebral block on postoperative pain and complications in patients undergoing open nephrectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Nephrectomy Pain Scores Paravertebral Block External Oblique Intercostal Block

Interventions

BupivacaineDRUG

Used for regional anesthesia during nephrectomy procedure (e.g., paravertebral or external oblique intercostal block)

morphineDRUG

Used for postoperative pain control via PCA device

paracetamolDRUG

Used as part of postoperative multimodal analgesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Aged 18 to 90 years * Scheduled for elective open radical nephrectomy for renal cell carcinoma * ASA classification I-III * Mini-Mental State Examination score ≥24 * Provided written informed consent Exclusion Criteria: * Neuropathy * Hepatic failure * Coagulopathy * Local anesthetic allergy * Mini-Mental State Examination score \<24 * Refusal to participate

Locations (1)

Hacettepe University Faculty of Medicine Hospital

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Postoperative Pain Score

Pain intensity measured using Visual Analog Scale at rest. (Visual Analog Scale ranging from 0 = no pain to 10 = worst pain imaginable; higher scores indicate worse pain).

Time frame: Up to 24 hours after surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.