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Results for “β-thalassemia Intermedia”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT07506863
What this trial is testing

Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Who this might be right for
Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 54
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT06421636
What this trial is testing

Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Who this might be right for
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals 19
Not applicableEnrolling By InvitationNCT06685536
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CS-101

Who this might be right for
Beta-Thalassemia
CorrectSequence Therapeutics Co., Ltd 5
Testing effectiveness (Phase 2)Study completedNCT00390858
What this trial is testing

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Who this might be right for
Transfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Ended earlyNCT01571635
What this trial is testing

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Who this might be right for
Beta Thalassemia MajorBeta Thalassemia Intermedia
Celgene 46
Early research (Phase 1)Ended earlyNCT04925206
What this trial is testing

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 8
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Early research (Phase 1)Looking for participantsNCT06465550
What this trial is testing

Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 9
Not applicableStudy completedNCT05506358
What this trial is testing

Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada

Who this might be right for
Sickle Cell DiseaseSickle Cell TraitBeta-Thalassemia+2 more
University of British Columbia 145
Large-scale testing (Phase 3)Study completedNCT06146478
What this trial is testing

Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Blood Care Clinic 200
Testing effectiveness (Phase 2)Study completedNCT04054921
What this trial is testing

Safety Study for Beta Thalassemia Subjects on PTG-300

Who this might be right for
β-thalassemiaIneffective Erythropoiesis
Protagonist Therapeutics, Inc. 34
Very early researchLooking for participantsNCT05745532
What this trial is testing

Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients

Who this might be right for
β-thalassemia
Shenzhen Hemogen 10
Post-approval studies (Phase 4)UnknownNCT05462548
What this trial is testing

The Safety and Efficiency of Luspatercept in Chinese Adults With Transfusion Dependent β-thalassemia: a Real-world Study

Who this might be right for
Thalassemia MajorTransfusion-dependent Anemia
Sun Yat-sen University 20
Testing effectiveness (Phase 2)Study completedNCT01749540
What this trial is testing

Study to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002)

Who this might be right for
B-Thalassemia
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 64
Not applicableLooking for participantsNCT06314529
What this trial is testing

Long-term Follow-up Study of BHC001 for TDT

Who this might be right for
Thalassemia, Beta
Bioray Laboratories 6
Post-approval studies (Phase 4)Active Not RecruitingNCT05891249
What this trial is testing

Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

Who this might be right for
Anemia
Bristol-Myers Squibb 85
Large-scale testing (Phase 3)Enrolling By InvitationNCT04208529
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CTX001

Who this might be right for
Beta-ThalassemiaThalassemiaSickle Cell Disease+4 more
Vertex Pharmaceuticals Incorporated 160
Not applicableActive Not RecruitingNCT02633943
What this trial is testing

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Genetix Biotherapeutics Inc. 66
Testing effectiveness (Phase 2)Study completedNCT04364269
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia

Who this might be right for
Beta-ThalassemiaNon-transfusion-dependent Thalassemia
Vifor (International) Inc. 35
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