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Results for “5q Minus Syndrome”

35 trials

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Showing 20 of 35 results

Testing effectiveness (Phase 2)Ended earlyNCT01465386
What this trial is testing

Bortezomib in Treating Patients With High-Risk Acute Myeloid Leukemia in Remission

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Myeloblastic Leukemia Without Maturation (M1)+9 more
Fred Hutchinson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT01869114
What this trial is testing

Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+7 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 57
Testing effectiveness (Phase 2)UnknownNCT00885508
What this trial is testing

The Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q

Who this might be right for
Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaAcute Myeloid Leukemia
Groupe Francophone des Myelodysplasies 85
Large-scale testing (Phase 3)Active Not RecruitingNCT03223961
What this trial is testing

A Trial Testing Early vs Late Onset of EPO Alfa Treatment in Lower Risk MDS

Who this might be right for
Myelodysplastic Syndromes
Groupe Francophone des Myelodysplasies 124
Testing effectiveness (Phase 2)Study completedNCT00602771
What this trial is testing

Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed, Previously Untreated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)+14 more
National Cancer Institute (NCI) 84
Testing effectiveness (Phase 2)Study completedNCT01349972
What this trial is testing

Alvocidib, Cytarabine, and Mitoxantrone Hydrochloride or Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Monoblastic Leukemia (M5a)+13 more
National Cancer Institute (NCI) 172
Testing effectiveness (Phase 2)Study completedNCT00839982
What this trial is testing

Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDS

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+5 more
Fred Hutchinson Cancer Center 35
Large-scale testing (Phase 3)Study completedNCT01243476
What this trial is testing

Study of REVLIMID (Lenalidomide) Versus Placebo in Patients With Low Risk Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndrome
Fundación General de la Universidad de Salamanca 61
Testing effectiveness (Phase 2)Study completedNCT01273766
What this trial is testing

Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

Who this might be right for
Acute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+133 more
Wake Forest University Health Sciences 16
Testing effectiveness (Phase 2)Study completedNCT01338337
What this trial is testing

Study of Vidaza (Azacitidine) Versus Support Treatment in Patients With Low Risk Myelodysplastic Syndrome (Low and Intermediate-1 IPSS) Without the 5q Deletion and Transfusion Dependent Anaemia

Who this might be right for
Myelodysplastic Syndrome (MDS)
Asociación Andaluza de Hematología y Hemoterapia 40
Testing effectiveness (Phase 2)Study completedNCT00004997
What this trial is testing

Leucovorin for the Treatment of 5 q Minus Syndrome

Who this might be right for
5q Minus SyndromeMyelodysplastic Syndrome
National Institutes of Health Clinical Center (CC) 14
Not applicableStudy completedNCT00112593
What this trial is testing

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in Remission+176 more
Fred Hutchinson Cancer Center 5
Testing effectiveness (Phase 2)Study completedNCT00795002
What this trial is testing

Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)+14 more
National Cancer Institute (NCI) 78
Not applicableStudy completedNCT01872819
What this trial is testing

Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay

Who this might be right for
Adult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Monoblastic Leukemia (M5a)+16 more
University of Washington 16
Not applicableUnknownNCT04701229
What this trial is testing

Haploinsufficiency of the RBM22 and SLU7 Genes in Del(5q) Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic SyndromesMyelodysplastic Syndrome With Isolated Del(5Q)Myelodysplastic Syndrome With Del(5Q)
University Hospital, Brest 100
Early research (Phase 1)Study completedNCT00101296
What this trial is testing

Tipifarnib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Erythroid Leukemia (M6)Adult Acute Megakaryoblastic Leukemia (M7)+16 more
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)Study completedNCT00322101
What this trial is testing

Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAcute Myeloid Leukemia/Transient Myeloproliferative DisorderAdult Acute Myeloid Leukemia in Remission+16 more
Fred Hutchinson Cancer Center 25
Large-scale testing (Phase 3)Study completedNCT02085408
What this trial is testing

Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)+14 more
ECOG-ACRIN Cancer Research Group 727
Testing effectiveness (Phase 2)Study completedNCT02019069
What this trial is testing

CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Adult Acute Erythroid Leukemia (M6)Adult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)+13 more
Rondeep Brar 11
Testing effectiveness (Phase 2)Study completedNCT02666950
What this trial is testing

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic Syndrome With Isolated Del(5q)Myelodysplastic/Myeloproliferative Neoplasm+3 more
Mayo Clinic 3
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