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Results for “AK112”

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Testing effectiveness (Phase 2)Looking for participantsNCT07669779
What this trial is testing

A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Advanced Non Small Cell Lung Cancer (NSCLC)
Akeso 348
Testing effectiveness (Phase 2)Looking for participantsNCT06802666
What this trial is testing

Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal CancerNeoadjuvant Therapy
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 45
Large-scale testing (Phase 3)Active Not RecruitingNCT06591520
What this trial is testing

AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
Akeso 682
Large-scale testing (Phase 3)Active Not RecruitingNCT05499390
What this trial is testing

AK112 in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Advanced Non-small-cell Lung Cancer
Akeso 398
Testing effectiveness (Phase 2)Looking for participantsNCT06637007
What this trial is testing

Phase II Clinical Trial of Chidamide Combined With AK112 for Second-line and Advanced Bone and Soft Tissue Sarcoma

Who this might be right for
Sarcoma,Soft TissueSarcomaSarcoma of Bone
Shanxi Province Cancer Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07712094
What this trial is testing

AK112 Combination Therapy as First Line Treatment for Metastatic Digestive System Neuroendocrine Cancer

Who this might be right for
Neuroendocrine Cancer
Tianjin Medical University Cancer Institute and Hospital 56
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07767994
What this trial is testing

AK112 Combined With GAP Conversion Therapy for Locally Advanced Gallbladder Cancer

Who this might be right for
Gallbladder Cancer
First Affiliated Hospital Xi'an Jiaotong University 22
Testing effectiveness (Phase 2)Study completedNCT05432492
What this trial is testing

AK112 in Patients With Unresectable Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
Akeso 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06646055
What this trial is testing

AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Ductal Adenocarcinoma
Akeso 110
Testing effectiveness (Phase 2)Active Not RecruitingNCT05951608
What this trial is testing

A Phase Ib/II Clinical Study of AK127 in Combination With AK112 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Akeso 216
Testing effectiveness (Phase 2)Active Not RecruitingNCT05247684
What this trial is testing

AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC

Who this might be right for
Resectable Non-small Cell Lung Cancer
Akeso 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT05904379
What this trial is testing

AK112 and AK104 With or Without Chemotherapy in Advanced Non-small Cell Lung Cancer

Who this might be right for
Advanced Non-small-cell Lung Cancer
Akeso 233
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06537011
What this trial is testing

AK112 Plus AP Regimen for Operable Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Neoadjuvant Therapy of Operable Locally Advanced Head and Neck Squamous Cell Carcinoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06684873
What this trial is testing

A Multicenter, Single-arm, Open-label Study Evaluating the Safety and Efficacy of AK112 Combined With Chemotherapy as First-line Treatment for Non-squamous NSCLC Patients With BRAIN Metastases and Negative Driver Genes (IVO BRAIN)

Who this might be right for
NSCLCBrain Metastasases
Sun Yat-sen University 55
Early research (Phase 1)Not Yet RecruitingNCT06913218
What this trial is testing

MRNA Vaccines AK154 Monotherapy or in Combination With AK104/AK112,and Sequential mFOLFIRINOX in Surgically Resected PDAC

Who this might be right for
Pancreas CancerPancreas Cancer, Duct Cell Adenocarcinoma
Akeso 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05846867
What this trial is testing

A Phase Ib/II Clinical Study on AK112 Combined or Not Combined With AK119 in pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer
Akeso 170
Testing effectiveness (Phase 2)Study completedNCT06478043
What this trial is testing

Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for SCLC

Who this might be right for
Small-cell Lung Cancer
Zhejiang Cancer Hospital 60
Early research (Phase 1)Study completedNCT04047290
What this trial is testing

AK112, a PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors

Who this might be right for
Neoplasms Malignant
Akesobio Australia Pty Ltd 80
Testing effectiveness (Phase 2)Looking for participantsNCT06951646
What this trial is testing

CtDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)

Who this might be right for
Non Small Cell Lung CancerImmune Checkpoint Inhibitors (ICIs)
Second Xiangya Hospital of Central South University 70
Testing effectiveness (Phase 2)Study completedNCT05214482
What this trial is testing

AK112 in Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
Akeso 154
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