Not applicableNot Yet RecruitingNCT06586801What this trial is testingThe Patient-Reported Outcomes in ALK Positive Advanced NSCLC in ChinaWho this might be right forNon-small Cell Lung Cancer Shanghai East Hospital 800
Testing effectiveness (Phase 2)Looking for participantsNCT05456256What this trial is testingLP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung AdenocarcinomaWho this might be right forAdenocarcinoma of LungCarcinoma, Non-Small-Cell Lung Lantern Pharma Inc. 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06682884What this trial is testingLorlatinib as Neoadjuvant Treatment in Stage IB-IIIB ALK-rearranged Non-Small Cell Lung CancerWho this might be right forNeoadjuvant Non-Small Cell Lung Cancer Peking University People's Hospital 25
Not applicableNot Yet RecruitingNCT06652555What this trial is testingThe Incidence and Risk Factors of Central Nervous System Adverse Events of Lorlatinib in Patients with ALK-positive Advanced Non-small Cell Lung Cancer: a Real-world StudyWho this might be right forALKNSCLC Shanghai Pulmonary Hospital, Shanghai, China 100
Not applicableLooking for participantsNCT07633626What this trial is testingVortioxetine for Cognitive Function in ALK-positive NSCLC Treated With LorlatinibWho this might be right forAdvanced ALK/ROS1-positive NSCLCCarcinoma, Non-Small-Cell Lung (NSCLC)Lung Adenocarcinoma+3 more Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo 24
Large-scale testing (Phase 3)Ended earlyNCT02775006What this trial is testingDocetaxel Versus Intercalated Erlotinib-docetaxel in Patients With Relapsed EGFR Wild Type, ALK Negative Non Squamous Cell CarcinomaWho this might be right forCarcinoma, Non-small Cell Lung The Netherlands Cancer Institute 45
Not applicableUnknownNCT03647111What this trial is testingReal World Study of First Line Crizotinib for ALK Rearranged Non-squamous Non-small Cell Lung CancerWho this might be right forNon-small Cell Lung Cancer Hunan Province Tumor Hospital 120
Not applicableNo Longer AvailableNCT02784158What this trial is testingAn Expanded Access Study of Brigatinib for Patients With ALK-positive Advanced Non-Small Cell Lung CancerWho this might be right forNon-small Cell Lung CancerLung CancerAdvanced Malignancies+1 more Ariad Pharmaceuticals
Testing effectiveness (Phase 2)Ended earlyNCT04323436What this trial is testingStudy of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping MutationsWho this might be right forCarcinoma, Non-Small-Cell Lung Novartis Pharmaceuticals 31
Not applicableStudy completedNCT01300429What this trial is testingMolecular Determinants of Acquired Clinical Resistance to Crizotinib in Non-small Cell Lung Cancer Harboring a Translocation or Inversion Event Involving the ALK Gene LocusWho this might be right forLung Cancer Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT06007937What this trial is testingLorlatinib in Combination With Ramucirumab in People With Lung CancerWho this might be right forNon Small Cell Lung CancerMetastaticRecurrent Memorial Sloan Kettering Cancer Center 9
Testing effectiveness (Phase 2)Study completedNCT03088930What this trial is testingEvaluating Crizotinib in the Neoadjuvant Setting in Patients With Non-small Cell Lung CancerWho this might be right forLung Cancer, Nonsmall Cell University of Colorado, Denver 3
Not applicableStudy completedNCT02304406What this trial is testingRetrospective Epidemiology Study Of ALK Rearrangement In Non-Small Cell Lung Cancer Patients In The Middle East & North AfricaWho this might be right forNon-small Cell Lung Cancer Pfizer 449
Early research (Phase 1)Study completedNCT00585195What this trial is testingOral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced CancerWho this might be right forNon-Small Cell Lung Cancer ALK-positiveNon-Small Cell Lung Cancer c-Met DependentNon-Small Cell Lung Cancer ROS Marker Positive+2 more Pfizer 596
Testing effectiveness (Phase 2)Active Not RecruitingNCT05845671What this trial is testingAmivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET AlterationsWho this might be right forLung CancerNon Small Cell Lung Cancer University of Colorado, Denver 12
Not applicableAvailableNCT06834074What this trial is testingExpanded Access Program of Neladalkib (NVL-655) for Patients With Advanced ALK+ NSCLC or Other ALK+ Solid TumorsWho this might be right forNon Small Cell Lung CancerALK-positive Non-small Cell Lung Cancer (NSCLC) Nuvalent Inc.
Testing effectiveness (Phase 2)Study completedNCT01945021What this trial is testingPhase II Safety and Efficacy Study of Crizotinib in East Asian Patients With ROS1 Positive, ALK Negative Advanced NSCLCWho this might be right forNon Small Cell Lung CancerROS1 Proto OncogeneCrizotinib Pfizer 129
Testing effectiveness (Phase 2)Looking for participantsNCT07360743What this trial is testingImmunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 LevelsWho this might be right forNon Small Cell Lung Cancer (Squamous or Non Squamous) UNICANCER 275
Not applicableStudy completedNCT02042105What this trial is testingA Prospective Epidemiologic Study of ALK-Positive NSCLC in ChinaWho this might be right forNon-small-cell Lung Cancer Guangdong Association of Clinical Trials 3,649
Large-scale testing (Phase 3)Study completedNCT02352948What this trial is testingA Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung CancerWho this might be right forNon - Small Cell Lung Cancer NSCLC AstraZeneca 597