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Results for “ALK Translocation”

23 trials

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Showing 20 of 23 results

Large-scale testing (Phase 3)Study completedNCT01639001
What this trial is testing

Crizotinib Versus Chemotherapy In Previously Untreated ALK Positive East Asian Non-Small Cell Lung Cancer Patients

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Pfizer 207
Post-approval studies (Phase 4)Ended earlyNCT03672643
What this trial is testing

Long Term Safety Observation of Crizotinib in Chinese NSCLC Population

Who this might be right for
ALK or ROS1-positive NSCLC
Pfizer 41
Post-approval studies (Phase 4)Looking for participantsNCT05525338
What this trial is testing

Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels

Who this might be right for
Drug MonitoringCarcinoma, Non-Small-Cell LungLung Cancer+2 more
University Medical Center Groningen 196
Testing effectiveness (Phase 2)Study completedNCT01945021
What this trial is testing

Phase II Safety and Efficacy Study of Crizotinib in East Asian Patients With ROS1 Positive, ALK Negative Advanced NSCLC

Who this might be right for
Non Small Cell Lung CancerROS1 Proto OncogeneCrizotinib
Pfizer 129
Testing effectiveness (Phase 2)WithdrawnNCT01500824
What this trial is testing

A Clinical Study Testing The Safety And Efficacy Of Crizotinib In East Asian Patients With Anaplastic Lymphoma Kinase (ALK) Positive Advanced Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Pfizer
Large-scale testing (Phase 3)UnknownNCT03991403
What this trial is testing

Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Samsung Medical Center 228
Early research (Phase 1)Study completedNCT02292550
What this trial is testing

Study of Safety and Efficacy of LEE011 and Ceritinib in Patients With ALK-positive Non-small Cell Lung Cancer.

Who this might be right for
Non-small Cell Lung Cancer
Novartis Pharmaceuticals 27
Not applicableUnknownNCT04921553
What this trial is testing

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)

Who this might be right for
CancerCancer MetastaticNTRK Gene Fusion Overexpression+13 more
Centre Leon Berard 500
Not applicableActive Not RecruitingNCT04881916
What this trial is testing

Immune and Genomic Markers in ALK+ NSCLC

Who this might be right for
Anaplastic Lymphoma Kinase Gene TranslocationNon-Small Cell Lung Cancer
Massachusetts General Hospital 100
Testing effectiveness (Phase 2)UnknownNCT02946359
What this trial is testing

A+C in Metastatic Lung Adenocarcinoma Cancer

Who this might be right for
Lung Adenocarcinoma Metastatic
Chinese PLA General Hospital 60
Testing effectiveness (Phase 2)Ended earlyNCT02186821
What this trial is testing

Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE)

Who this might be right for
Tumors With Aberrations in ALK or ROS1
Novartis Pharmaceuticals 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT04223596
What this trial is testing

Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients

Who this might be right for
Lung CancerNSCLCNSCLC Stage IIIB+1 more
Fundación GECP 33
Large-scale testing (Phase 3)Study completedNCT01154140
What this trial is testing

A Clinical Trial Testing The Efficacy Of Crizotinib Versus Standard Chemotherapy Pemetrexed Plus Cisplatin Or Carboplatin In Patients With ALK Positive Non Squamous Cancer Of The Lung

Who this might be right for
Non Squamous Lung Cancer
Pfizer 343
Testing effectiveness (Phase 2)Ended earlyNCT01228435
What this trial is testing

IPI-504 in NSCLC Patients With ALK Translocations

Who this might be right for
Lung CancerStage IIIb Lung CancerStage IV Lung Cancer
Massachusetts General Hospital 3
Not applicableStudy completedNCT02679170
What this trial is testing

Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)

Who this might be right for
Non-Small Cell Lung Cancer
Pfizer 692
Large-scale testing (Phase 3)Study completedNCT00932893
What this trial is testing

An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Pfizer 347
Not applicableStudy completedNCT01300429
What this trial is testing

Molecular Determinants of Acquired Clinical Resistance to Crizotinib in Non-small Cell Lung Cancer Harboring a Translocation or Inversion Event Involving the ALK Gene Locus

Who this might be right for
Lung Cancer
Memorial Sloan Kettering Cancer Center 30
Not applicableUnknownNCT05110950
What this trial is testing

Endobronchial Ultrasound Needle Aspiration With and Without Suction

Who this might be right for
Mediastinal LymphadenopathyHilar LymphadenopathyLymphoma+7 more
Università Politecnica delle Marche 306
Large-scale testing (Phase 3)Active Not RecruitingNCT02201992
What this trial is testing

Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)

Who this might be right for
ALK Gene RearrangementALK Gene TranslocationALK Positive+5 more
ECOG-ACRIN Cancer Research Group 166
Testing effectiveness (Phase 2)UnknownNCT04292119
What this trial is testing

Lorlatinib Combinations in Lung Cancer

Who this might be right for
Lung CancerAnaplastic Lymphoma Kinase Gene TranslocationROS1 Rearrangement+4 more
Massachusetts General Hospital 96
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