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Results for “AML and High Risk MDS”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Not applicableLooking for participantsNCT07183878
What this trial is testing

Venetoclax-Enhanced BUCY vs. Standard BUCY Conditioning in High-Risk AML and MDS Patients Undergoing Allo-HSCT (Ven-BUCY Study)

Who this might be right for
Acute Myeloid LeukemiaHigh-Risk Acute Myeloid LeukemiaMyelodysplastic Syndromes+1 more
First Affiliated Hospital of Zhejiang University 138
Testing effectiveness (Phase 2)Looking for participantsNCT03214562
What this trial is testing

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
High Risk Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
M.D. Anderson Cancer Center 116
Testing effectiveness (Phase 2)UnknownNCT00838240
What this trial is testing

Clofarabine, Cytarabine, and Idarubicin in Treating Patients With Intermediate-Risk or High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplasia

Who this might be right for
LeukemiaMyelodysplastic Syndromes
European Organisation for Research and Treatment of Cancer - EORTC 114
Testing effectiveness (Phase 2)Study completedNCT00143559
What this trial is testing

Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies

Who this might be right for
LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
St. Jude Children's Research Hospital 17
Early research (Phase 1)Ended earlyNCT04477291
What this trial is testing

CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Aptose Biosciences Inc. 45
Large-scale testing (Phase 3)Study completedNCT00454480
What this trial is testing

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
LeukemiaMyelodysplastic Syndromes
The University of New South Wales 2,000
Early research (Phase 1)Ended earlyNCT05275439
What this trial is testing

Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Shattuck Labs, Inc. 106
Early research (Phase 1)Ended earlyNCT00049582
What this trial is testing

Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+10 more
National Cancer Institute (NCI) 36
Large-scale testing (Phase 3)Study completedNCT00008359
What this trial is testing

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Who this might be right for
Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02775903
What this trial is testing

An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 213
Testing effectiveness (Phase 2)Looking for participantsNCT07155226
What this trial is testing

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

Who this might be right for
Acute Lymphoblastic LeukaemiaAcute Myeloid LeukaemiaHigher-risk Myelodysplastic Syndromes
AstraZeneca 84
Testing effectiveness (Phase 2)Looking for participantsNCT07532824
What this trial is testing

Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)/AMLProton Therapy+2 more
Institute of Hematology and Blood Transfusion, Czech Republic 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07153497
What this trial is testing

Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
National Cancer Institute (NCI) 132
Early research (Phase 1)Looking for participantsNCT06297941
What this trial is testing

Study of REM-422 in Patients With AML or Higher Risk MDS

Who this might be right for
Myelodysplastic SyndromesHigher Risk Myelodysplastic SyndromesAcute Myeloid Leukemia+1 more
Remix Therapeutics 100
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Not applicableStudy completedNCT02007863
What this trial is testing

Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia

Who this might be right for
LeukemiaMyelodysplasiaAcute Lymphocytic Leukemia+1 more
University of Miami 2
Early research (Phase 1)Study completedNCT02649764
What this trial is testing

Prexasertib (LY2606368), Cytarabine, and Fludarabine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaRecurrent Acute Myeloid LeukemiaRecurrent High Risk Myelodysplastic Syndrome+2 more
M.D. Anderson Cancer Center 15
Early research (Phase 1)Active Not RecruitingNCT03613532
What this trial is testing

Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+2 more
Jacqueline Garcia, MD 102
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