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Results for “APOL1-mediated Kidney Disease”

7 trials

Showing 7 of 7 results

Early research (Phase 1)Study completedNCT05324410
What this trial is testing

Dose Escalation Study to Evaluate Safety and Pharmacokinetics (PK) of VX-840 in Healthy Participants

Who this might be right for
APOL1-mediated Kidney Disease
Vertex Pharmaceuticals Incorporated 88
Not applicableLooking for participantsNCT06839833
What this trial is testing

APOL1 Genotyping CTA Clinical Performance Study

Who this might be right for
APOL1-mediated Kidney Disease
Almac Diagnostic Services LLC 1,000
Large-scale testing (Phase 3)Looking for participantsNCT05312879
What this trial is testing

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease

Who this might be right for
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated 466
Testing effectiveness (Phase 2)Looking for participantsNCT06794996
What this trial is testing

Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease With or Without Comorbidities

Who this might be right for
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated 45
Testing effectiveness (Phase 2)Looking for participantsNCT06824987
What this trial is testing

Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

Who this might be right for
APOL1-Mediated Kidney Disease
AstraZeneca 96
Testing effectiveness (Phase 2)Study completedNCT04340362
What this trial is testing

Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis

Who this might be right for
Glomerulosclerosis, Focal Segmental
Vertex Pharmaceuticals Incorporated 16
Testing effectiveness (Phase 2)Looking for participantsNCT06830629
What this trial is testing

MZE829 in Adults With APOL1 Kidney Disease

Who this might be right for
Proteinuric Kidney Disease
Maze Therapeutics 56

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