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Results for “ATM Gene Mutation”

26 trials

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Showing 20 of 26 results

Early research (Phase 1)Looking for participantsNCT06177171
What this trial is testing

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

Who this might be right for
BRCA1 MutationBRCA2 MutationBRCA Mutation+3 more
Pamela Munster 18
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Not applicableLooking for participantsNCT05420064
What this trial is testing

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Who this might be right for
BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more
Memorial Sloan Kettering Cancer Center 1,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT06033092
What this trial is testing

Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion

Who this might be right for
BRCA MutationPALB2 Gene MutationDuctal Carcinoma in Situ+6 more
European Institute of Oncology 200
Testing effectiveness (Phase 2)Study completedNCT03377556
What this trial is testing

Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
ATM Gene MutationATR Gene MutationBARD1 Gene Mutation+18 more
SWOG Cancer Research Network 51
Not applicableEnded earlyNCT02857894
What this trial is testing

Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated)

Who this might be right for
Choroidal Neovascularization
Fondation Ophtalmologique Adolphe de Rothschild 7
Not applicableStudy completedNCT04425200
What this trial is testing

Prevalence of HRR-related Genes Mutations and Prognosis in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients in Real World Setting

Who this might be right for
Prostatic Neoplasms
AstraZeneca 205
Not applicableLooking for participantsNCT02775461
What this trial is testing

Pancreas Registry and High Risk Registry

Who this might be right for
Pancreas CancerPancreatitisChronic Pancreatitis+3 more
Icahn School of Medicine at Mount Sinai 1,368
Testing effectiveness (Phase 2)Ended earlyNCT03442556
What this trial is testing

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

Who this might be right for
ATM Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+7 more
University of Washington 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07215416
What this trial is testing

Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T)

Who this might be right for
Ataxia Telangiectasia
Timothy Yu 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT02286687
What this trial is testing

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

Who this might be right for
Advanced Malignant NeoplasmATM Gene MutationBRCA1 Gene Mutation+5 more
M.D. Anderson Cancer Center 150
Early research (Phase 1)Looking for participantsNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Testing effectiveness (Phase 2)Study completedNCT02401347
What this trial is testing

Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors

Who this might be right for
Advanced Breast CancerHER2/Neu NegativeTriple-Negative Breast Cancer
Melinda Telli 21
Large-scale testing (Phase 3)Looking for participantsNCT02000089
What this trial is testing

The Cancer of the Pancreas Screening-5 CAPS5)Study

Who this might be right for
Pancreas CancerPeutz-Jeghers Syndrome (PJS)Gene Mutation+2 more
Johns Hopkins University 9,000
Not applicableLooking for participantsNCT05097274
What this trial is testing

The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.

Who this might be right for
Prostate CancerBRCA MutationMismatch Repair Gene Mutation+4 more
Institute of Cancer Research, United Kingdom 50
Testing effectiveness (Phase 2)Study completedNCT03962114
What this trial is testing

Effects of Vitamin B3 in Patients With Ataxia Telangiectasia

Who this might be right for
Ataxia TelangiectasiaATM Gene Mutation
Radboud University Medical Center 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03344965
What this trial is testing

Olaparib In Metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerInvasive Breast CancerSomatic Mutation Breast Cancer (BRCA1)+7 more
Beth Israel Deaconess Medical Center 114
Early research (Phase 1)Ended earlyNCT06337630
What this trial is testing

A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Institut Curie 10
Not applicableStudy completedNCT03075735
What this trial is testing

Prospective Multicentre Cohort Study PROREPAIR-B (mCRPC)

Who this might be right for
Prostate Cancer
Centro Nacional de Investigaciones Oncologicas CARLOS III 408
Testing effectiveness (Phase 2)Study completedNCT03009682
What this trial is testing

Olaparib Monotherapy in Relapsed Small Cell Lung Cancer Patients With HR Pathway Gene Mutations Not Limited to BRCA 1/2 Mutations, ATM Deficiency or MRE11A Mutations

Who this might be right for
Small Cell Lung Cancer
Samsung Medical Center 15
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