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Results for “ATTR Amyloidosis Wild Type”

41 trials

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Showing 20 of 41 results

Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
Testing effectiveness (Phase 2)Ended earlyNCT03702829
What this trial is testing

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Who this might be right for
Amyloidosis
Brigham and Women's Hospital 31
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 15
Very early researchStudy completedNCT05023889
What this trial is testing

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Who this might be right for
PolyneuropathiesWild Type ATTR AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis+2 more
Austin Neuromuscular Center 10
Not applicableStudy completedNCT06261216
What this trial is testing

Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Amyloid CardiomyopathyWild Type ATTR Amyloidosis
Medical University of Graz 180
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Not applicableStudy completedNCT03966105
What this trial is testing

Prevalence of Wild Type ATTR

Who this might be right for
Wild-type Transthyretin Amyloidosis
Oncology Institute of Southern Switzerland 94
Not applicableStudy completedNCT03996382
What this trial is testing

Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Syndrome

Who this might be right for
Amyloidosis CardiacCarpal Tunnel Syndrome
Aarhus University Hospital Skejby 120
Not applicableUnknownNCT06186167
What this trial is testing

Amyloidosis Incidence in High-Risk Cardiac Device Patients

Who this might be right for
AmyloidCardiac AmyloidosisAmyloidosis Cardiac+4 more
Midwest Heart & Vascular Specialists 100
Not applicableLooking for participantsNCT06836011
What this trial is testing

Study on Atrioventricular Regurgitation in Transthyretin Amyloid Cardiomyopathy: Definition, Prevalence, and Prognostic Impact.

Who this might be right for
ATTR Amyloidosis With CardiomyopathyATTR-CMATTR Amyloidosis Wild Type+2 more
Medical University of Vienna 600
Not applicableLooking for participantsNCT06465810
What this trial is testing

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Who this might be right for
Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more
AstraZeneca 1,850
Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,250
Not applicableUnknownNCT06015997
What this trial is testing

Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR

Who this might be right for
ATTR Amyloidosis Wild TypeSevere Aortic StenosisAortic Valve Stenosis+1 more
Jordan Collaborating Cardiology Group 100
Not applicableLooking for participantsNCT06458374
What this trial is testing

ATTR Cardiac Amyloidosis in a Selected Population

Who this might be right for
ATTR Amyloidosis Wild TypeATTR Gene MutationCarpal Tunnel Syndrome+1 more
Helse Møre og Romsdal HF 180
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Not applicableStudy completedNCT06029452
What this trial is testing

A Retrospective Validation Study To Identify Chart-Based Clinical Diagnosis Of Wild-Type Transthyretin Amyloid Cardiomyopathy (Attrwt-CM) And Non-Amyloid Heart Failure Among Patients With Heart Failure (HF).

Who this might be right for
ATTR-CM
Pfizer 558
Early research (Phase 1)Study completedNCT04601051
What this trial is testing

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
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