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Results for “Abnormal Liver Function”

161 trials

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Showing 20 of 161 results

Early research (Phase 1)Study completedNCT02184091
What this trial is testing

Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of Nevirapine

Who this might be right for
Renal InsufficiencyHepatic Insufficiency
Boehringer Ingelheim 41
Post-approval studies (Phase 4)Study completedNCT02050841
What this trial is testing

Octaplas Pediatric Plasma Replacement Trial

Who this might be right for
Liver SurgeryLiver DysfunctionCoagulopathy+1 more
Octapharma 50
Early research (Phase 1)Study completedNCT06444204
What this trial is testing

Evaluate the Effect of Mild and Moderate Hepatic Impairment on the Single-Dose Pharmacokinetics of Rilzabrutinib (PRN1008)

Who this might be right for
Hepatic Function AbnormalHealthy Volunteers
Principia Biopharma, a Sanofi Company 29
Early research (Phase 1)Study completedNCT05765344
What this trial is testing

Study of Bulevirtide in Participants Who Have Normal or Impaired Liver Function

Who this might be right for
Hepatic ImpairmentHealthy
Gilead Sciences 74
Not applicableStudy completedNCT02992639
What this trial is testing

Weight Loss Effect on Circulating Liver Enzymes

Who this might be right for
Visceral FatLiver Dysfunction
Yonsei University 80
Testing effectiveness (Phase 2)Study completedNCT01307098
What this trial is testing

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Who this might be right for
Cholesterol Ester Storage Disease(CESD)Lysosomal Acid Lipase DeficiencyLAL-Deficiency
Alexion Pharmaceuticals, Inc. 9
Early research (Phase 1)Study completedNCT00674024
What this trial is testing

Pazopanib to Treat Adults With Advanced Cancers and Varying Degrees of Liver Function

Who this might be right for
NeoplasmsLymphoma
National Cancer Institute (NCI) 8
Testing effectiveness (Phase 2)Ended earlyNCT00550849
What this trial is testing

Study to Assess the Safety, Tolerability, and Pharmacodynamics of RTA 402 in Patients With Hepatic Dysfunction

Who this might be right for
Liver Disease
Biogen 16
Early research (Phase 1)Study completedNCT05718258
What this trial is testing

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 26
Early research (Phase 1)Looking for participantsNCT06577415
What this trial is testing

RAY1225 in Participants With Impaired Liver Function

Who this might be right for
Hepatic Impairment
Guangdong Raynovent Biotech Co., Ltd 24
Early research (Phase 1)Study completedNCT00741273
What this trial is testing

Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults

Who this might be right for
Impaired Liver Function
Repros Therapeutics Inc. 16
Early research (Phase 1)Study completedNCT05440344
What this trial is testing

Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Who this might be right for
Hepatic InsufficiencyHealthy
Eli Lilly and Company 27
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT04511507
What this trial is testing

CytoSorb in Patients With Liver Failure

Who this might be right for
Liver Dysfunction
Institutul Clinic Fundeni 35
Post-approval studies (Phase 4)WithdrawnNCT05275907
What this trial is testing

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

Who this might be right for
High Blood PressureLiver TransplantRenal Function Abnormal
Northwestern University
Not applicableLooking for participantsNCT07343037
What this trial is testing

Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care

Who this might be right for
Hepatic InsufficiencyCirrhosis, Liver
University Hospital, Strasbourg, France 100
Not applicableNot Yet RecruitingNCT06178302
What this trial is testing

DEscripitive Patient Analysis to Enable Risk-based Quality Improvement Measures in a lArge iNternal mediCIne grouP Practice

Who this might be right for
Liver DysfunctionThyroidAtherosclerosis+3 more
Imed19 1,000
Early research (Phase 1)Study completedNCT06908954
What this trial is testing

The Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose

Who this might be right for
Hepatic ImpairmentHealthy
Ipsen 31
Not applicableStudy completedNCT06403553
What this trial is testing

FC Change From Day 1 to Day 3 Associated With SALD

Who this might be right for
Liver Dysfunction
Chinese Medical Association 96
Early research (Phase 1)Study completedNCT03890809
What this trial is testing

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Who this might be right for
Liver DysfunctionHealthy Volunteers
Bristol-Myers Squibb 32
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