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Results for “Acute Leukemias of Ambiguous Lineage”

36 trials

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Showing 20 of 36 results

Early research (Phase 1)Study completedNCT03194932
What this trial is testing

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Who this might be right for
Acute Myeloid Leukemia
St. Jude Children's Research Hospital 62
Testing effectiveness (Phase 2)Looking for participantsNCT06013423
What this trial is testing

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+7 more
Fred Hutchinson Cancer Center 54
Testing effectiveness (Phase 2)Study completedNCT01858740
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more
Fred Hutchinson Cancer Center 20
Testing effectiveness (Phase 2)Study completedNCT03012672
What this trial is testing

Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaMyeloid Neoplasm
University of Washington 50
Testing effectiveness (Phase 2)Looking for participantsNCT04065399
What this trial is testing

Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Lineage Acute Leukemia+2 more
Syndax Pharmaceuticals 447
Testing effectiveness (Phase 2)Study completedNCT02135874
What this trial is testing

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+5 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Looking for participantsNCT06317662
What this trial is testing

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 153
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Not applicableStudy completedNCT02551718
What this trial is testing

High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia+3 more
University of Washington 34
Early research (Phase 1)Looking for participantsNCT06177067
What this trial is testing

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Refractory Acute Myeloid LeukemiaRelapsed Acute Myeloid LeukemiaAcute Leukemia of Ambiguous Lineage
St. Jude Children's Research Hospital 24
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Not applicableNot Yet RecruitingNCT06991920
What this trial is testing

Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage

Who this might be right for
Adult ALLMPAL
Institute of Hematology & Blood Diseases Hospital, China 50
Testing effectiveness (Phase 2)Looking for participantsNCT04329728
What this trial is testing

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

Who this might be right for
Lymphoid Malignancies
AVM Biotechnology Inc 144
Testing effectiveness (Phase 2)Study completedNCT02828358
What this trial is testing

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
National Cancer Institute (NCI) 78
Testing effectiveness (Phase 2)Looking for participantsNCT06355583
What this trial is testing

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial

Who this might be right for
Acute Lymphoblastic LeukaemiaAcute Leukemia of Ambiguous LineageChronic Myeloid Leukemia+3 more
Imperial College London 50
Not applicableNot Yet RecruitingNCT07094750
What this trial is testing

Randomization for the Identification of Best Treatment Intensity for Less Fit Adults With Acute Myeloid Leukemia and Myeloid Neoplasms

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaMyeloid Neoplasm
Fred Hutchinson Cancer Center 50
Testing effectiveness (Phase 2)Study completedNCT02220985
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+20 more
Fred Hutchinson Cancer Center 84
Early research (Phase 1)Ended earlyNCT00933985
What this trial is testing

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineageAcute Undifferentiated LeukemiaAngioimmunoblastic T-cell Lymphoma+26 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Looking for participantsNCT07046078
What this trial is testing

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia+1 more
Fred Hutchinson Cancer Center
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