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Results for “Acute Leukemias of Ambiguous Lineage”

36 trials

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Showing 20 of 36 results

Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Early research (Phase 1)Study completedNCT01319864
What this trial is testing

POETIC Plerixafor as a Chemosensitizing Agent for Relapsed Acute Leukemia and MDS in Pediatric Patients

Who this might be right for
Relapsed/Refractory AMLRelapsed/Refractory ALLSecondary AML/MDS+3 more
Seattle Children's Hospital 20
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Looking for participantsNCT06575296
What this trial is testing

Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

Who this might be right for
Acute LeukemiaAcute Leukemia of Ambiguous LineageAcute Lymphoblastic Leukemia+5 more
City of Hope Medical Center 27
Testing effectiveness (Phase 2)Looking for participantsNCT05901974
What this trial is testing

Venetoclax Combined With Azactidine in the Treatment of ALAL

Who this might be right for
Acute Leukemia of Ambiguous Lineage
Sheng-Li Xue, MD 23
Testing effectiveness (Phase 2)Looking for participantsNCT04440267
What this trial is testing

Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage

Who this might be right for
Acute Leukemia of Ambiguous Lineage
Institute of Hematology & Blood Diseases Hospital, China 50
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Testing effectiveness (Phase 2)Study completedNCT02220985
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+20 more
Fred Hutchinson Cancer Center 84
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Large-scale testing (Phase 3)Study completedNCT01371656
What this trial is testing

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Who this might be right for
Acute Leukemias of Ambiguous LineageBacterial InfectionDiarrhea+7 more
Children's Oncology Group 624
Early research (Phase 1)Looking for participantsNCT06177067
What this trial is testing

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Refractory Acute Myeloid LeukemiaRelapsed Acute Myeloid LeukemiaAcute Leukemia of Ambiguous Lineage
St. Jude Children's Research Hospital 24
Early research (Phase 1)Study completedNCT01431664
What this trial is testing

AT9283 in Treating Young Patients With Relapsed or Refractory Acute Leukemia

Who this might be right for
Leukemia
Cancer Research UK 7
Testing effectiveness (Phase 2)Looking for participantsNCT04065399
What this trial is testing

Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Lineage Acute Leukemia+2 more
Syndax Pharmaceuticals 447
Early research (Phase 1)Study completedNCT02141828
What this trial is testing

Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Gene

Who this might be right for
LeukemiaAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+1 more
Epizyme, Inc. 18
Early research (Phase 1)WithdrawnNCT05521087
What this trial is testing

JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias

Who this might be right for
Acute LeukemiasAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+1 more
Janssen Research & Development, LLC
Testing effectiveness (Phase 2)Study completedNCT02135874
What this trial is testing

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+5 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Looking for participantsNCT04329728
What this trial is testing

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

Who this might be right for
Lymphoid Malignancies
AVM Biotechnology Inc 144
Not applicableNot Yet RecruitingNCT07094750
What this trial is testing

Randomization for the Identification of Best Treatment Intensity for Less Fit Adults With Acute Myeloid Leukemia and Myeloid Neoplasms

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaMyeloid Neoplasm
Fred Hutchinson Cancer Center 50
Early research (Phase 1)Study completedNCT03194932
What this trial is testing

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Who this might be right for
Acute Myeloid Leukemia
St. Jude Children's Research Hospital 62
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