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Results for “Acute Leukemias of Ambiguous Lineage”

37 trials

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Showing 20 of 37 results

Early research (Phase 1)Looking for participantsNCT06177067
What this trial is testing

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Refractory Acute Myeloid LeukemiaRelapsed Acute Myeloid LeukemiaAcute Leukemia of Ambiguous Lineage
St. Jude Children's Research Hospital 24
Early research (Phase 1)Ended earlyNCT00933985
What this trial is testing

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineageAcute Undifferentiated LeukemiaAngioimmunoblastic T-cell Lymphoma+26 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07636564
What this trial is testing

Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative+1 more
SWOG Cancer Research Network 90
Not applicableLooking for participantsNCT07094750
What this trial is testing

Randomization for the Identification of Best Treatment Intensity for Less Fit Adults With Acute Myeloid Leukemia and Myeloid Neoplasms

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaMyeloid Neoplasm
Fred Hutchinson Cancer Center 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Testing effectiveness (Phase 2)Looking for participantsNCT06355583
What this trial is testing

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial

Who this might be right for
Acute Lymphoblastic LeukaemiaAcute Leukemia of Ambiguous LineageChronic Myeloid Leukemia+3 more
Imperial College London 50
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT02828358
What this trial is testing

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
National Cancer Institute (NCI) 78
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Not applicableNot Yet RecruitingNCT06991920
What this trial is testing

Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage

Who this might be right for
Adult ALLMPAL
Institute of Hematology & Blood Diseases Hospital, China 50
Early research (Phase 1)Study completedNCT01319864
What this trial is testing

POETIC Plerixafor as a Chemosensitizing Agent for Relapsed Acute Leukemia and MDS in Pediatric Patients

Who this might be right for
Relapsed/Refractory AMLRelapsed/Refractory ALLSecondary AML/MDS+3 more
Seattle Children's Hospital 20
Early research (Phase 1)Study completedNCT01431664
What this trial is testing

AT9283 in Treating Young Patients With Relapsed or Refractory Acute Leukemia

Who this might be right for
Leukemia
Cancer Research UK 7
Testing effectiveness (Phase 2)Looking for participantsNCT06013423
What this trial is testing

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+7 more
Fred Hutchinson Cancer Center 54
Testing effectiveness (Phase 2)Study completedNCT01858740
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more
Fred Hutchinson Cancer Center 20
Testing effectiveness (Phase 2)Looking for participantsNCT04329728
What this trial is testing

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

Who this might be right for
Lymphoid Malignancies
AVM Biotechnology Inc 144
Early research (Phase 1)Study completedNCT01132573
What this trial is testing

Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineagePhiladelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Looking for participantsNCT05901974
What this trial is testing

Venetoclax Combined With Azactidine in the Treatment of ALAL

Who this might be right for
Acute Leukemia of Ambiguous Lineage
Sheng-Li Xue, MD 23
Testing effectiveness (Phase 2)Study completedNCT02220985
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+20 more
Fred Hutchinson Cancer Center 84
Early research (Phase 1)Active Not RecruitingNCT04898894
What this trial is testing

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Acute Leukemia of Ambiguous Lineage in RelapseAcute Myeloid Leukemia, in RelapseRefractory Acute Leukemia of Ambiguous Lineage+1 more
St. Jude Children's Research Hospital 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT04067336
What this trial is testing

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Advanced Malignant NeoplasmAcute Myeloid LeukemiaMixed Lineage Leukemia+4 more
Kura Oncology, Inc. 263
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