Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Adjunctive Treatment of Major Depressive Disorder (MDD)”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT01670279
What this trial is testing

Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 18
Testing effectiveness (Phase 2)Looking for participantsNCT06633016
What this trial is testing

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

Who this might be right for
Major Depressive Disorder
Autobahn Therapeutics, Inc. 230
Large-scale testing (Phase 3)Ended earlyNCT01121536
What this trial is testing

Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Who this might be right for
Depression
Cephalon 867
Testing effectiveness (Phase 2)Study completedNCT00481195
What this trial is testing

Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Who this might be right for
Bipolar I Depression
Cephalon 257
Not applicableStudy completedNCT04770285
What this trial is testing

Trial to Evaluate the Effectiveness of a Digital Therapeutics in Adults Diagnosed With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 386
Testing effectiveness (Phase 2)Study completedNCT02805439
What this trial is testing

Efficacy and Safety of S 47445 Versus Placebo as Adjunctive Treatment in Depressed Patients Not Fully Recovered From Depressive Symptoms With a Current Antidepressant Treatment

Who this might be right for
Major Depressive Disorder
Institut de Recherches Internationales Servier 400
Testing effectiveness (Phase 2)Study completedNCT00797966
What this trial is testing

Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 850
Large-scale testing (Phase 3)Study completedNCT00876343
What this trial is testing

Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Co., Ltd. 586
Large-scale testing (Phase 3)Study completedNCT01360645
What this trial is testing

Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial)

Who this might be right for
Depressive DisorderDepressionDepressive Disorder, Major+2 more
Otsuka Pharmaceutical Development & Commercialization, Inc. 826
Large-scale testing (Phase 3)Study completedNCT01072929
What this trial is testing

Evaluate the Efficacy and Safety of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Who this might be right for
Depression
Cephalon 433
Testing effectiveness (Phase 2)Study completedNCT04103892
What this trial is testing

CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

Who this might be right for
Adjunctive Treatment of Major Depressive Disorder
Clexio Biosciences Ltd. 146
Not applicableEnded earlyNCT04712968
What this trial is testing

Efficacy of Daylight as Adjunctive Treatment in Patients With Depression

Who this might be right for
Unipolar Depression
University of Aarhus 12
Large-scale testing (Phase 3)Study completedNCT02196506
What this trial is testing

Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress

Who this might be right for
Depressive DisorderDepressionDepressive Disorder, Major+2 more
Otsuka Pharmaceutical Development & Commercialization, Inc. 837
Post-approval studies (Phase 4)WithdrawnNCT05504486
What this trial is testing

Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety

Who this might be right for
Major Depressive Disorder (MDD)
Otsuka Pharmaceutical Development & Commercialization, Inc.
Testing effectiveness (Phase 2)Study completedNCT04466345
What this trial is testing

Semaglutide for the Treatment of Cognitive Dysfunction in Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
University Health Network, Toronto 72
Testing effectiveness (Phase 2)Study completedNCT01447576
What this trial is testing

Study of Safety & Tolerability of OPC-34712 as Adjunctive Therapy in Treatment of Adult Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 1,036
Large-scale testing (Phase 3)Not Yet RecruitingNCT07775300
What this trial is testing

Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder

Who this might be right for
Depressive Disorder, Major
Eli Lilly and Company 1,000
Large-scale testing (Phase 3)Study completedNCT04985942
What this trial is testing

Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Intra-Cellular Therapies, Inc. 485
Testing effectiveness (Phase 2)Study completedNCT06340958
What this trial is testing

CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder

Who this might be right for
Adjunctive Treatment of Major Depressive Disorder (MDD)
Clexio Biosciences Ltd. 99
Not applicableStudy completedNCT07804979
What this trial is testing

Comparison of Efficacy of Minocyclin and Celecoxib as Adjunctive Treatment in Treatment Resistant Cases of Major Depressive Disorder

Who this might be right for
Major Depressive Disorder (MDD)Treatment-resistant Depression (TRD)
Lahore General Hospital 78
Next Page