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Results for “Adult Hypophosphatasia”

22 trials

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Showing 20 of 22 results

Not applicableLooking for participantsNCT07390240
What this trial is testing

The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia

Who this might be right for
Hypophosphatasia
AstraZeneca 55
Not applicableStudy completedNCT03418389
What this trial is testing

Evaluate and Monitor Physical Performance of Adults Treated With Asfotase Alfa for Hypophosphatasia

Who this might be right for
Hypophosphatasia
Dr. Lothar Seefried 23
Not applicableStudy completedNCT04195763
What this trial is testing

Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 50
Not applicableUnknownNCT04018287
What this trial is testing

Circulating miRNAs and Bone Microstructure in Adults With Hypophosphatasia

Who this might be right for
HypophosphatasiaBone Diseases, MetabolicBone
Medical University of Vienna 60
Testing effectiveness (Phase 2)Looking for participantsNCT07179640
What this trial is testing

Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1

Who this might be right for
Hypophosphatasia (HPP)
Alesta Therapeutics 120
Not applicableStudy completedNCT02291497
What this trial is testing

Burden of Disease in Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Wuerzburg University Hospital 114
Testing effectiveness (Phase 2)Study completedNCT01406977
What this trial is testing

Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Ultragenyx Pharmaceutical Inc 8
Not applicableUnknownNCT04222452
What this trial is testing

The PORTRAIT Study

Who this might be right for
Hypophosphatasia
Sheffield Teaching Hospitals NHS Foundation Trust 14
Testing effectiveness (Phase 2)Study completedNCT05890794
What this trial is testing

Pilot Trial of Single Dose Ilofotase Alfa in Hypophosphatasia

Who this might be right for
Hypophosphatasia
AM-Pharma 12
Not applicableUnknownNCT06161142
What this trial is testing

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology

Who this might be right for
Hypophosphatasia
University of Bonn 60
Post-approval studies (Phase 4)WithdrawnNCT04189315
What this trial is testing

Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Early research (Phase 1)Study completedNCT04980248
What this trial is testing

Study of ALXN1850 in Participants With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 15
Not applicableLooking for participantsNCT02237625
What this trial is testing

Natural History Study of Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Duke University 200
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)Study completedNCT01163149
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 19
Not applicableUnknownNCT04181164
What this trial is testing

Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Hvidovre University Hospital 30
Testing effectiveness (Phase 2)Study completedNCT02797821
What this trial is testing

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 27
Large-scale testing (Phase 3)Active Not RecruitingNCT06079281
What this trial is testing

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 124
Early research (Phase 1)Study completedNCT00739505
What this trial is testing

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 6
Not applicableLooking for participantsNCT05596539
What this trial is testing

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

Who this might be right for
Hypophosphatasia
Assistance Publique - Hôpitaux de Paris 130
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