Early research (Phase 1)Looking for participantsNCT04485013What this trial is testingTTX-080 HLA-G Antagonist in Subjects With Advanced CancersWho this might be right forCancer Tizona Therapeutics, Inc 240
Testing effectiveness (Phase 2)Looking for participantsNCT05086692What this trial is testingA Beta-only IL-2 ImmunoTherapY StudyWho this might be right forAdvanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Ended earlyNCT01120275What this trial is testingGamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV MelanomaWho this might be right forAcral Lentiginous Malignant MelanomaLentigo Maligna Malignant MelanomaNodular Malignant Melanoma+4 more National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)UnknownNCT03955354What this trial is testingPD-1 Antibody SHR-1210 Combined With Apatinib of First-line Treatment of Advanced Acral MelanomaWho this might be right forMelanoma Peking University Cancer Hospital & Institute 30
Testing effectiveness (Phase 2)Study completedNCT02071940What this trial is testingPLX3397 KIT in Acral aNd mucOsal MelanomaWho this might be right forMalignant Melanoma The Christie NHS Foundation Trust 7
Testing effectiveness (Phase 2)Study completedNCT02875132What this trial is testingPembrolizumab in Advanced/Metastatic Acral Lentiginous MelanomaWho this might be right forAcral Lentiginous Melanoma Chinese University of Hong Kong 9
Testing effectiveness (Phase 2)WithdrawnNCT02535078What this trial is testingPhase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Advanced Cutaneous MelanomaWho this might be right forMalignant Melanoma Immunocore Ltd
Testing effectiveness (Phase 2)Ended earlyNCT02978443What this trial is testingA Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With IpilimumabWho this might be right forAcral Lentiginous MelanomaMucosal Melanoma Georgetown University 14
Testing effectiveness (Phase 2)Looking for participantsNCT06797297What this trial is testingEvaluate the Efficacy and Safety of IBI363 Monotherapy Compared to Pembrolizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal or Acral Melanoma Who Had Not Previously Received Systemic TherapyWho this might be right forMelanoma Innovent Biologics (Suzhou) Co. Ltd. 180
Early research (Phase 1)Looking for participantsNCT05098210What this trial is testingPersonalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung CancerWho this might be right forAnatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Cutaneous Melanoma+22 more Fred Hutchinson Cancer Center 25
Large-scale testing (Phase 3)Looking for participantsNCT05549297What this trial is testingTebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)Who this might be right forAdvanced Melanoma Immunocore Ltd 540
Testing effectiveness (Phase 2)UnknownNCT04397770What this trial is testingCamrelizumab Plus Apatinib and Temozolomide as First Line Therapy in Advanced Acral MelanomaWho this might be right forMelanoma Peking University Cancer Hospital & Institute 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04462406What this trial is testingUsing Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop TrialWho this might be right forAdvanced MelanomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+8 more ECOG-ACRIN Cancer Research Group 150
Testing effectiveness (Phase 2)UnknownNCT05087602What this trial is testingToripalimab Combined With Anlotinib in Unresectable Locally Advanced or Metastatic Acral Malignant MelanomaWho this might be right forLocally Advanced or Metastatic Acral Malignant Melanoma Qilu Hospital of Shandong University 29
Testing effectiveness (Phase 2)UnknownNCT03991975What this trial is testingStudy of TQB2450 Combined With Anlotinib in Subjects With Advanced Acral Malignant MelanomaWho this might be right forAdvanced Acral Malignant Melanoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 42
Early research (Phase 1)Ended earlyNCT02346955What this trial is testingStudy of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001)Who this might be right forNon-small Cell Lung Carcinoma (NSCLC)MelanomaBladder Cancer+3 more Famewave Ltd. 27
Testing effectiveness (Phase 2)UnknownNCT03454919What this trial is testingEfficacy of Palbociclib in Advanced Acral Melanoma With Cell Cycle Gene AberrationsWho this might be right forMelanoma Peking University Cancer Hospital & Institute 60
Testing effectiveness (Phase 2)Study completedNCT01395121What this trial is testingA Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has SpreadWho this might be right forMucosal Lentiginous MelanomaAcral Lentiginous Malignant Melanoma Institute of Cancer Research, United Kingdom 29
Early research (Phase 1)Ended earlyNCT04244552What this trial is testingA Phase 1b Trial of ATRC-101 in Adults With Advanced Solid MalignanciesWho this might be right forBreast CancerColorectal CancerOvarian Cancer+13 more Atreca, Inc. 87
Testing effectiveness (Phase 2)Study completedNCT00700882What this trial is testingDasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryWho this might be right forMelanoma (Skin) Eastern Cooperative Oncology Group 81