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Results for “Advanced Esophageal Adenocarcinoma”

354 trials

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Showing 20 of 354 results

Early research (Phase 1)Study completedNCT04641871
What this trial is testing

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 78
Early research (Phase 1)Study completedNCT00537121
What this trial is testing

Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer

Who this might be right for
Esophageal CancerGastric CancerLiver Cancer
Roswell Park Cancer Institute 23
Testing effectiveness (Phase 2)Looking for participantsNCT04984733
What this trial is testing

Temozolomide + Nivolumab in MGMT Methylated Oesophagogastric Cancer

Who this might be right for
Adenocarcinoma - GEJCancer of Esophagus
University of Southampton 18
Testing effectiveness (Phase 2)Study completedNCT00016900
What this trial is testing

PNU-93914 in Treating Patients With Locally Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT00493025
What this trial is testing

Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery

Who this might be right for
Esophageal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 19
Early research (Phase 1)Study completedNCT00003548
What this trial is testing

Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity

Who this might be right for
Cancer
NYU Langone Health 20
Large-scale testing (Phase 3)Looking for participantsNCT07221149
What this trial is testing

Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Who this might be right for
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Bristol-Myers Squibb 690
Testing effectiveness (Phase 2)Study completedNCT01212822
What this trial is testing

Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer

Who this might be right for
Adenocarcinoma of the EsophagusAdenocarcinoma of the Gastroesophageal JunctionDiffuse Adenocarcinoma of the Stomach+17 more
Fox Chase Cancer Center 20
Early research (Phase 1)Active Not RecruitingNCT06607185
What this trial is testing

The Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

Who this might be right for
Pancreatic Ductal AdenocarcinomaNon-small Cell Lung CancerColorectal Cancer+2 more
Eli Lilly and Company 750
Large-scale testing (Phase 3)Looking for participantsNCT06203600
What this trial is testing

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Who this might be right for
Advanced Esophageal AdenocarcinomaAdvanced Gastric AdenocarcinomaAdvanced Gastroesophageal Junction Adenocarcinoma+13 more
National Cancer Institute (NCI) 224
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Early research (Phase 1)Study completedNCT03538028
What this trial is testing

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Who this might be right for
Cervical CancerMicrosatellite Instability (MSI)-High Endometrial CancerGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+14 more
Incyte Biosciences International Sàrl 22
Not applicableNot Yet RecruitingNCT07191405
What this trial is testing

Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors

Who this might be right for
ImmunotherapyChemotherapy
Second Affiliated Hospital, School of Medicine, Zhejiang University 156
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Not applicableStudy completedNCT00477919
What this trial is testing

E-MOSAIC Electronic Tool to Monitor Symptoms

Who this might be right for
Cancer
Swiss Cancer Institute 264
Large-scale testing (Phase 3)UnknownNCT01523015
What this trial is testing

Efficacy and Safety Study of the Combined Modality Therapy in Adenocarcinoma of the Esophago-gastric Junction

Who this might be right for
Adenocarcinoma of the Gastroesophageal Junction
Medical University of Lublin 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439110
What this trial is testing

Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 38
Not applicableActive Not RecruitingNCT06504615
What this trial is testing

Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France

Who this might be right for
Gastric AdenocarcinomaGastro-esophageal Junction AdenocarcinomaEsophageal Adenocarcinoma (EAC)+1 more
Bristol-Myers Squibb 208
Early research (Phase 1)UnknownNCT03507998
What this trial is testing

Phase 1 Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal Tumors

Who this might be right for
Colorectal AdenocarcinomaGastric AdenocarcinomaPancreatic Adenocarcinoma+4 more
Curegenix Inc. 39
Very early researchStudy completedNCT03395847
What this trial is testing

Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma

Who this might be right for
Advanced Gastroesophageal Junction AdenocarcinomaClinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+22 more
M.D. Anderson Cancer Center 9
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