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Results for “Advanced Gastrointestinal Stromal Tumors”

139 trials

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Showing 20 of 139 results

Early research (Phase 1)Study completedNCT00083213
What this trial is testing

Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Cancer
Regeneron Pharmaceuticals 25
Early research (Phase 1)Study completedNCT00654160
What this trial is testing

Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer

Who this might be right for
Anal CancerCarcinoma of the AppendixColorectal Cancer+9 more
Mayo Clinic 7
Not applicableAvailableNCT06948955
What this trial is testing

Expanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Gastrointestinal Stromal Tumors

Who this might be right for
Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc.
Testing effectiveness (Phase 2)Study completedNCT00006357
What this trial is testing

STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma

Who this might be right for
Endometrial CancerGastrointestinal Stromal TumorOvarian Cancer+2 more
European Organisation for Research and Treatment of Cancer - EORTC 91
Testing effectiveness (Phase 2)Looking for participantsNCT07096609
What this trial is testing

Lenvatinib After Progression on Imatinib, Sunitinib, and Regorafenib for GIST Patients

Who this might be right for
GIST
Asan Medical Center 48
Testing effectiveness (Phase 2)Ended earlyNCT02452424
What this trial is testing

A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma of the Head and Neck+2 more
Daiichi Sankyo 78
Testing effectiveness (Phase 2)Ended earlyNCT05160168
What this trial is testing

THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Who this might be right for
Gastrointestinal Stromal Tumors (GIST)Neoplasms, Connective TissueNeoplasms, Connective and Soft Tissue+6 more
Theseus Pharmaceuticals 32
Testing effectiveness (Phase 2)Looking for participantsNCT07434843
What this trial is testing

PH 2 Pemigatinib in SDH-deficient GIST

Who this might be right for
SDH Gene MutationGastrointestinal Stromal Tumor
Dana-Farber Cancer Institute 24
Testing effectiveness (Phase 2)Study completedNCT03944304
What this trial is testing

Paclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib.

Who this might be right for
Gastrointestinal Stromal Tumors
Asan Medical Center 40
Testing effectiveness (Phase 2)Study completedNCT01243346
What this trial is testing

Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene

Who this might be right for
D842-related Mutant GIST
Arog Pharmaceuticals, Inc. 20
Early research (Phase 1)Looking for participantsNCT06655246
What this trial is testing

Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Who this might be right for
Gastrointestinal Stromal Tumor (GIST)Gastrointestinal Stromal CancerGastrointestinal Stromal Neoplasm+2 more
Kura Oncology, Inc. 157
Large-scale testing (Phase 3)Study completedNCT03353753
What this trial is testing

Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer Therapies

Who this might be right for
Gastrointestinal Stromal Tumors
Deciphera Pharmaceuticals, LLC 129
Testing effectiveness (Phase 2)Study completedNCT02401815
What this trial is testing

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Who this might be right for
Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc. 51
Testing effectiveness (Phase 2)UnknownNCT02365441
What this trial is testing

A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST)

Who this might be right for
Gastrointestinal Stromal Tumour
Australasian Gastro-Intestinal Trials Group 78
Testing effectiveness (Phase 2)Study completedNCT04633122
What this trial is testing

Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib

Who this might be right for
Gastrointestinal Stromal Tumor(GIST)
Zai Lab (Shanghai) Co., Ltd. 108
Not applicableStudy completedNCT00477919
What this trial is testing

E-MOSAIC Electronic Tool to Monitor Symptoms

Who this might be right for
Cancer
Swiss Cancer Institute 264
Early research (Phase 1)Study completedNCT04908176
What this trial is testing

A Drug-drug Interaction Study of Avapritinib and Midazolam

Who this might be right for
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more
Blueprint Medicines Corporation 10
Testing effectiveness (Phase 2)Study completedNCT00003103
What this trial is testing

Chemotherapy in Treating Patients With Solid Tumors

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+7 more
Memorial Sloan Kettering Cancer Center 57
Not applicableStudy completedNCT06321055
What this trial is testing

An Observational Study to Learn More About Treatment With Regorafenib in People With Advanced Gastrointestinal Stromal Tumors in the United States

Who this might be right for
Advanced Gastrointestinal Stromal Tumor
Bayer 136
Testing effectiveness (Phase 2)Study completedNCT02607332
What this trial is testing

Paclitaxel in Patients With Metastatic or Advanced Gastrointestinal Stromal Tumors (GIST) After Failure to Imatinib and Sunitinib

Who this might be right for
Gastrointestinal Stromal Tumors
Asan Medical Center 25
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