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Results for “Advanced NRAS-Mutant Melanoma”

16 trials

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Showing 16 of 16 results

Early research (Phase 1)Temporarily pausedNCT03932253
What this trial is testing

MEK Inhibitor FCN-159 To Treat Advanced Melanoma With NRAS-aberrant (Ia) and NRAS-mutant (Ib)or NF1-mutant(1b)

Who this might be right for
Melanoma
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 79
Testing effectiveness (Phase 2)Looking for participantsNCT07449754
What this trial is testing

Belvarafenib in Combination With Cobimetinib in Patients With Locally Advanced or Metastatic NRAS-Mutant Melanoma

Who this might be right for
Advanced or Metastatic Melanoma
Hanmi Pharmaceutical Company Limited 45
Early research (Phase 1)Study completedNCT03415126
What this trial is testing

ASN007 in Patients With Advanced Solid Tumors

Who this might be right for
CancerMalignancyNeoplasia+16 more
Asana BioSciences 49
Testing effectiveness (Phase 2)Ended earlyNCT03580382
What this trial is testing

Study of CDX-3379, a Human Monoclonal Antibody Targeting ERBB3, in Combination With the MEK Inhibitor, Trametinib, in Patients With Advanced Stage NRAS Mutant and BRAF/NRAS Wildtype (WT) Melanoma

Who this might be right for
Melanoma
NYU Langone Health 3
Early research (Phase 1)Ended earlyNCT03114319
What this trial is testing

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Who this might be right for
Advanced EGFR Mutant Non Small Cell LungCancer (NSCLC)KRAS G12-mutant NSCLCEsophageal Squamous Cell Cancer (SCC)+4 more
Novartis Pharmaceuticals 227
Early research (Phase 1)Ended earlyNCT02974725
What this trial is testing

A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma

Who this might be right for
Non-Small Cell Lung CancerMelanoma
Novartis Pharmaceuticals 241
Testing effectiveness (Phase 2)Study completedNCT04059224
What this trial is testing

TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma

Who this might be right for
Stage IV MelanomaStage III Melanoma
Universitair Ziekenhuis Brussel 45
Testing effectiveness (Phase 2)Study completedNCT03973151
What this trial is testing

Study of HL-085 in NRAS Mutant Advanced Melanoma

Who this might be right for
Melanoma
Shanghai Kechow Pharma, Inc. 42
Testing effectiveness (Phase 2)Study completedNCT01781572
What this trial is testing

A Phase Ib/II Study of LEE011 in Combination With MEK162 in Patients With NRAS Mutant Melanoma

Who this might be right for
Locally Advanced or Metastatic NRAS Mutant Melanoma
Pfizer 102
Large-scale testing (Phase 3)Looking for participantsNCT06008106
What this trial is testing

Comparing Tunlametinib Capsules and Combination Chemotherapy in Advanced NRAS-mutant Melanoma

Who this might be right for
Melanoma
Shanghai Kechow Pharma, Inc. 165
Large-scale testing (Phase 3)Active Not RecruitingNCT06346067
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

Who this might be right for
Advanced or Metastatic NRAS-mutant Melanoma
Erasca, Inc. 78
Early research (Phase 1)Active Not RecruitingNCT04835805
What this trial is testing

Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-mutant Advanced Melanoma.

Who this might be right for
Melanoma
Genentech, Inc. 65
Testing effectiveness (Phase 2)Study completedNCT01320085
What this trial is testing

A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma

Who this might be right for
BRAF or NRAS Mutant Metastatic Melanoma
Pfizer 183
Post-approval studies (Phase 4)Looking for participantsNCT07445022
What this trial is testing

RWS of Tunlametinib in NRAS-Mutant Advanced Melanoma

Who this might be right for
Melanoma Advanced
Fudan University 110
Testing effectiveness (Phase 2)Study completedNCT06208124
What this trial is testing

IMM-6-415 in RAS/RAF Mutant Solid Tumors

Who this might be right for
Advanced Solid Tumor (Phase 1)Pancreas AdenocarcinomaNon-small Cell Lung Cancer+1 more
Immuneering Corporation 30
Early research (Phase 1)Looking for participantsNCT07584226
What this trial is testing

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

Who this might be right for
Advanced NRAS-Mutant MelanomaAdvanced NRAS-Mutant Solid TumorsNRAS Mutation+8 more
Relay Therapeutics, Inc. 35