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Results for “Advanced Rectal Adenocarcinoma”

592 trials

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Showing 20 of 592 results

Early research (Phase 1)Study completedNCT03629756
What this trial is testing

Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Who this might be right for
Non-small Cell Lung CancerSquamous Cell Carcinoma of the Head and NeckBreast Cancer+9 more
Arcus Biosciences, Inc. 48
Not applicableStudy completedNCT04670445
What this trial is testing

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

Who this might be right for
Stage IV MelanomaAdvanced Lung CancerStage IV Non-Small Cell Lung Cancer+19 more
Massachusetts General Hospital 199
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Not applicableNot Yet RecruitingNCT07689812
What this trial is testing

Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Carcinoma)+12 more
Natera, Inc. 920
Testing effectiveness (Phase 2)Looking for participantsNCT07198165
What this trial is testing

SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC

Who this might be right for
Rectal CancerRectal AdenocarcinomaRectal Cancer, Radiotherapy+6 more
Ruijin Hospital 104
Testing effectiveness (Phase 2)Looking for participantsNCT06937177
What this trial is testing

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

Who this might be right for
Cancer Weight Loss
Endevica Bio 120
Testing effectiveness (Phase 2)Looking for participantsNCT06128551
What this trial is testing

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma
Revolution Medicines, Inc. 534
Testing effectiveness (Phase 2)Study completedNCT05104567
What this trial is testing

SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

Who this might be right for
Oesophageal Squamous Cell CarcinomaGastric CancerHepatocellular Carcinoma+2 more
Sanofi 138
Not applicableStudy completedNCT00950144
What this trial is testing

Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer

Who this might be right for
Colorectal CancerDepressionFatigue+3 more
City of Hope Medical Center 123
Not applicableActive Not RecruitingNCT05524012
What this trial is testing

Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer

Who this might be right for
Locally Advanced Rectal CarcinomaNeoadjuvant TreatmentRadiotherapy+1 more
Jena University Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT07750951
What this trial is testing

Single-arm, Phase II Clinical Study Evaluating the Safety and Efficacy of Sintilimab Combined With IBI-310 and Chemotherapy as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Who this might be right for
MSI-H/dMMR Locally Advanced Rectal Adenocarcinoma
Xijing Hospital 34
Testing effectiveness (Phase 2)Looking for participantsNCT06793137
What this trial is testing

Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, Adenocarcinoma
AC Camargo Cancer Center 100
Early research (Phase 1)Active Not RecruitingNCT06147037
What this trial is testing

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Who this might be right for
Advanced Solid TumorMetastatic Colorectal CarcinomaHead and Neck Squamous Cell Carcinoma+4 more
AstraZeneca 13
Early research (Phase 1)Ended earlyNCT02908451
What this trial is testing

AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+1 more
AbGenomics B.V Taiwan Branch 39
Large-scale testing (Phase 3)Study completedNCT00766155
What this trial is testing

Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC 1,094
Early research (Phase 1)Ended earlyNCT04042480
What this trial is testing

SGN-CD228A in Advanced Solid Tumors

Who this might be right for
Cutaneous MelanomaPleural MesotheliomaHER2 Negative Breast Neoplasms+3 more
Seagen Inc. 88
Testing effectiveness (Phase 2)Study completedNCT02611024
What this trial is testing

Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors

Who this might be right for
Advanced Solid TumorsGlioblastomaSoft Tissue Sarcoma (Excluding GIST)+9 more
PharmaMar 316
Large-scale testing (Phase 3)Looking for participantsNCT05752136
What this trial is testing

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma

Who this might be right for
Rectal Cancer
Sir Run Run Shaw Hospital 108
Testing effectiveness (Phase 2)Temporarily pausedNCT05591534
What this trial is testing

Endorectal Brachytherapy for Rectal Cancer

Who this might be right for
Locally Advanced Rectal Carcinoma
University Hospital, Bordeaux 31
Early research (Phase 1)Active Not RecruitingNCT05382364
What this trial is testing

Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002)

Who this might be right for
Metastatic HER2+ Advanced Breast CancerBreast NeoplasmsGastric or Gastroesophageal Junction Adenocarcinoma (GEC)+1 more
Pfizer 25
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